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The Human Upgrade with Dave Asprey

The Real Reason You Still Feel Tired—Even When Your Bloodwork Looks Perfect | Dr Pompa : 1273

The Human Upgrade with Dave Asprey

Dave Asprey

Fat, Health & Fitness, Meditation, Biohacking, Lifestyle, Diet, Science, Self-improvement, Fasting, Nutrition, Hacking, Fitness, Brain, Wellness, Education

4.67.3K Ratings

🗓️ 24 April 2025

⏱️ 83 minutes

🧾️ Download transcript

Summary

Your bloodwork looks normal. Your doctor says you’re fine. But you still feel exhausted, inflamed, anxious—or worse. 

In this episode, Dave Asprey talks with Dr. Daniel Pompa, a leading voice in cellular detox and root-cause healing, to expose the hidden stressors hijacking your energy, hormones, and metabolism—even when your labs say you’re healthy. 

Dr. Pompa shares his personal health collapse and reveals how cellular dysfunction, neurotoxicity, and hormone resistance drive the chronic fatigue epidemic. If you’ve ever felt dismissed by “perfect” bloodwork, this conversation will rewire how you think about sickness—and show you how to reclaim real, lasting wellness. 


What You’ll Learn in This Episode: 

• Why your bloodwork can be “perfect” while your cells are on fire 

• The overlooked hormone resistances sabotaging your energy and metabolism 

• The 3-legged stool of chronic illness—and what actually drives disease 

• What “upstream detox” really means, and why most cleanses make you worse 

• Why toxins trigger genetic expression (and how to shut that down) 

• How to fix unexplainable fatigue, anxiety, and weight gain from the inside out 

• Why true healing starts with fixing the cell, not the symptom 


It’s time to stop chasing symptoms—and start upgrading from the root. 


**Check out Dr. Pompas EXCLUSIVE protocol built for The Human Upgrade listeners at davetestkit.com and use code ‘10OFF’ for a discount!** 

 

SPONSORS 

-Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  

-Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. 


 

Resources:  

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ 

Dr. Pompa’s Website –  https://drpompa.com/ 

Dr. Pompa’s Instagram - https://www.instagram.com/drpompa/?hl=en 

2025 Biohacking Conference: https://biohackingconference.com/2025 

Danger Coffee: https://dangercoffee.com 

Dave Asprey’s Website: https://daveasprey.com 

Dave Asprey’s Linktree: https://linktr.ee/daveasprey 

Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com 

Own an Upgrade Labs: https://ownanupgradelabs.com 

Upgrade Labs: https://upgradelabs.com 

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com 


Timestamps: 

• 00:00 Trailer 

• 00:55 Intro 

• 01:10 Healthy Is the New Sick 

• 02:27 Bloodwork & Hormone Resistance 

• 04:32 Dr. Pompa’s Health Collapse 

• 08:38 Toxins & Environmental Triggers 

• 15:01 Why Most Detox Fails 

• 29:16 The 5 Rs of Cellular Healing 

• 37:06 Olive Oil: Cure or Concern? 

• 38:11 Fat Balance for Energy 

• 42:13 Cholesterol & Saturated Fat 

• 46:26 Restoring Cellular Energy 

• 51:08 The Power of Diet Variation 

• 56:57 Plant Toxins Explained 

• 01:03:28 Emotional & Spiritual Detox 

• 01:13:55 Final Thoughts 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Transcript

Click on a timestamp to play from that location

0:00.0

Healthy could be the new sick. Blood levels can be made normal and yet not feel well. So many people are having that exact experience because it's not so simple. How does someone know the recipe that made them sick? Because if you know that, maybe you can undo it. So my saying is if we fix the cell, we get well. A lot of people today are trying to solve their gut problem when they're in a mold problem or they have

0:21.4

an upstream heavy metal issue when your cells make energy in the mitochondria which is in our cells

0:26.4

they make toxic if you understood the microbiome that means all the bacteria that are on our hands

0:32.5

that protect us if it wasn't there we'd. Detox is about fixing what's broken there.

0:38.3

And it's in the cell, not the liver, not the kidney.

0:41.3

How do you go about fixing the cell?

0:43.3

I have my five hours, which is a roadmap to do this.

0:47.3

You're listening to the Human Upgrade with Dave Asprey.

0:54.7

Hey, real quick, if you've only been listening on your favorite podcast app, you're missing

0:59.5

half the fun.

1:00.7

Head on over to my YouTube channel.

1:02.0

I'm doing way more over there.

1:03.6

Full video podcast episodes weekly.

1:06.1

YouTube only videos and some wild extras you're not going to hear here.

1:09.9

Just search Dave Asperpir on youtube see you

1:11.8

there so dr dan pampa you said that a lot of disease a lot of aging is damage at the cellular level

1:22.6

and i think we have some agreement on that. Is healthy the new sick?

1:28.6

Is healthy the new sick?

1:30.7

Well, when you look at the statistics in this country, you might say that, actually.

1:35.4

I've never heard it put that way, but it's actually a brilliant statement because healthy could be the new sick.

1:41.5

And especially because it becomes so normal to them, a lower level

1:46.7

of living. It's kind of like someone dimming the lights outside the room. After a while,

...

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