4.8 • 1.2K Ratings
🗓️ 5 December 2024
⏱️ 24 minutes
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A new study finds poor metabolic health and low HDL is a greater predictor of coronary artery calcium than LDL cholesterol.
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Video & Links to study: https://bit.ly/3Zj56fA
Time Stamps:
0:00 Intro
0:30 LDL does not correlate with the degree of coronary artery plaque.
1:02 HDL is protective against coronary artery disease and plaquing.
2:10 Triglycerides correlate with diabetes, coronary artery disease and plaquing.
3:45 HDL size is highly predictive.
5:15 LDL, vLDL, and IDL had no strong association.
8:00 LDL may be lower with prediabetes and diabetes, reflecting imbalance.
12:10 HDL is increased by lifestyle.
13:00 Plaquing is more common in diabetics.
15:47 High triglycerides increase odds of metabolic disease by 100%.
18:00 The smaller HDL particles become, the less protective they are.
19:13 Coronary artery calcium is associated with HDL size, concentration and composition.
21:20 High HDL with low triglycerides is linked with better metabolic health.
23:10 Exercise increases the size and number of your protective HDL.
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0:00.0 | A new study found that LDL cholesterol does not strongly correlate with the degree of coronary |
0:05.4 | artery atherosclerosis. |
0:07.7 | This is a very important study. |
0:09.1 | I'm going to talk slow intentionally so that no messages get lost in translation. |
0:14.1 | This is a study that was just published in the International Journal of Cardiology involving |
0:18.2 | 5,000 patients that were normal glycemic, pre-diabetic, |
0:22.7 | or diabetic. And that was the first part of this study. They wanted to investigate and see |
0:27.2 | whether the degree of diabetes or prediabetes correlated with coronary artery calcium scores. |
0:33.5 | They also then wanted to see which diabetic-related biomarkers and lipid-related biomarkers were linked with the degree of coronary artery calcium scores. |
0:43.3 | So this is really fascinating. |
0:44.3 | Now, what they found is that LDL cholesterol was not correlated with the degree of coronary artery calcium placking. |
0:53.3 | Now, this is really important because, again, |
0:56.4 | most doctors like to monomoneically focus on lowering your LDL cholesterol. |
1:01.3 | But it turned out that HDL cholesterol, the so-called good cholesterol, |
1:06.1 | that is increased when you exercise, when you have a low-carb diet, |
1:09.5 | when you have healthier fats and less |
1:11.7 | processed sugar in your diet, your HCL generally increases. H.D.L, specifically the larger |
1:17.9 | buoyant H.D.L. were more protective against both metabolic disease, as well as the degree |
1:25.1 | of coronary artery placking. And again, they used a CT scan to look at the degree of severity and calcification in the |
1:33.1 | coronary arteries, including the left anterior descending coronary artery, the one that is known |
1:38.5 | as the widowmaker and highly susceptible to becoming plaqued and atherosclerotic and, again, |
1:43.9 | is correlated with major adverse cardiovascular |
... |
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