Up next, the big day for a Yale research scientist is fast approaching.

She was due to be married in about five days.

And then, she disappeared.

Is this a case of a runaway bride?

A Yale University graduate student who is supposed to get married this weekend has something vanished.

This image shows the last time she was seen on surveillance video.

On that day we saw Annie going in.

But she's never seen coming out.

You don't get in or out without being captured on camera.

People don't simply vanish.

Or do they? Yale is one of the oldest and most respected universities in America, founded in 1701.

The campus is dotted with beautiful buildings designed by generations of noted architects.

But few people would call the building known as Tenamastad distinctive.

In fact, it's designed not to attract attention.

Tenamestad is very nondescript, for reasons. It's a research facility.

So there are all types of highly confidential multi-million dollar research that is done

from foundations and organizations from throughout the world.

One of the Amistad researchers was Annie Lay, a 24-year-old doctoral student of great ambition and brain power.

She didn't go out much. of great ambition and brain power.

She didn't go out much.

She had a very strict routine of going to work at the lab,

her studies, and back home. On the morning of Tuesday, September 8, 2009,

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