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TED Talks Daily

The future diagnostic lab ... inside your body | Aaron Morris

TED Talks Daily

TED

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4.111.9K Ratings

🗓️ 7 June 2021

⏱️ 6 minutes

🧾️ Download transcript

Summary

We need an inside-out approach to how we diagnose disease, says immuno-engineer and TED Fellow Aaron Morris. Introducing cutting-edge medical research, he unveils implantable technology that gives real-time, continuous analysis of a patient's health at the molecular level. "We're creating a diagnostic lab inside your body," Morris says -- and it may pave the way to diagnosing and treating disease better and faster than ever before.

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Transcript

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0:00.0

Hi, it's Bryce Dallas Howard here, guest hosting today on TED Talks Daily.

0:09.1

Here's a talk from Ted Fellow and immunoengineer Aaron Morris.

0:13.8

He's innovating on the future of medical testing by diagnosing disease from devices within the body.

0:22.5

Ow!

0:24.6

As anyone who stubbed a toe in the dark or spent an hour searching for their keys knows,

0:29.9

we're often limited by what we can or cannot see.

0:33.8

In fact, even our own bodies can be black boxes.

0:37.5

Today, I want to take you through a vision of health care that scientists and engineers, myself included, are building.

0:43.4

We are creating a diagnostic lab inside your body that can provide a continuous analysis of your health so that we can better see what's happening in patients.

0:51.9

Currently, if someone is sick, we may diagnose them by using a

0:55.4

biopsy to bring disease tissue outside the body, where we can see it. We do this if we suspect,

1:01.2

for instance, that a growth might be cancerous. Unfortunately, this approach can't work all the time

1:06.3

because of two major problems. First, some tissues, like brains or spinal cords, can't be routinely

1:12.7

biopsied. And second, doctors often don't know which tissue is causing the problem, so they

1:17.4

don't know what to biopsy. So far, we've dealt with these issues using external medical tests,

1:23.0

like MRIs or blood tests. These provide a broad overview of the health of a patient, but they can't

1:28.8

see the molecular and cellular changes that occur within tissues, and they certainly can't

1:34.0

provide enough information to proactively treat patients before symptoms develop. This is unfortunate

1:39.6

because it's these invisible changes that ultimately cause disease. Our inability to measure these changes results in a disparity

1:46.8

between what we can see on a test and what we know is happening in patients.

1:51.1

Let's take multiple sclerosis as an example.

1:54.3

In MS, which is an autoimmune disease,

...

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