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Short Wave

The Evolution Of Cancer Treatment

Short Wave

NPR

Daily News, Nature, Life Sciences, Astronomy, Science, News

4.7 β€’ 6K Ratings

πŸ—“οΈ 4 March 2024

⏱️ 16 minutes

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Summary

Recently, the US Food and Drug Administration approved a first-of-its-kind cancer therapy to treat aggresive forms of skin cancer. It has us thinking of the long history of cancer. One of the first recorded mentions of cancer appears in an ancient Egyptian text from around 3000 B.C. And although we now know much more about how cancer begins β€” as a series of mutations in someone's DNA β€” it's a disease people are still grappling with how to cure cancers today. This episode, cancer epidemiologist Mariana Stern talks about cancer history and treatment today β€” plus, why some people are more prone to certain cancers and why that might matter for curing them.

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Transcript

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0:00.0

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0:08.5

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0:16.0

You're listening to shortwave from NPR.

0:22.0

Hi shortwaivers, Aaron Scott here, and today we're exploring a disease that has plagued humans since, well, the evolution of humans, cancer.

0:31.0

Which Cancer Epidemiiologist Mariana Stern says at its core is caused by mutations in our

0:37.8

DNA.

0:38.8

What typically happens is that one mutation happens and it stays there and then another one happens and then those

0:46.8

cells start to acquire certain characteristics that allow them to proliferate more than they should.

0:55.0

And that's how we end up having a mass of cells,

0:58.0

which is what we call a tumor.

1:00.0

And as long as the disease has been in recorded history, people have been trying to treat it.

1:05.2

From the first description of cancer in an Egyptian text thousands of years ago,

1:09.8

humans have tried using pace, salts, teas, and cauterization to care cancer, just to name a few.

1:16.0

One milestone came in the 1700s when an English surgeon connected cancer to a clear environmental cause. In this case, chimney sweep. and a minimum age for chimney sweeps. And although avoiding the hazard might prevent cancer,

1:35.6

if you got it, the options for actually treating cancer were pretty minimal.

1:40.8

Cancer was a death sentence. People would not be given a long time to animal. of Southern California. And she says that for a long time cancer was often treated

1:55.1

with surgery. So the idea was let's remove the cancer and and that will take care

2:00.4

of it but then it was recognized that just removing the cancer often did not cure people

2:05.8

because cancer cells were being left behind.

2:08.6

Left behind to potentially grow back.

2:11.8

Then around the turn of the 19th century, physicians discovered that radiation could treat

2:16.8

cancer, but in some cases it could also cause it.

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