meta_pixel
Tapesearch Logo
Log in
Short Wave

The Dubious Consent Question At The Heart Of The Human Genome Project

Short Wave

NPR

Daily News, Nature, Life Sciences, Astronomy, Science, News

4.7 β€’ 6K Ratings

πŸ—“οΈ 15 July 2024

⏱️ 16 minutes

🧾️ Download transcript

Summary

The Human Genome Project was a massive undertaking that took more than a decade and billions of dollars to complete. For it, scientists collected DNA samples from anonymous volunteers who were told the final project would be a mosaic of DNA. Instead, over two-thirds of the DNA comes from one person: RP11. No one ever told him. Science journalist Ashley Smart talks to host Emily Kwong about his recent investigation into the decision to make RP11 the major donor β€” and why unearthing this history matters to genetics today.

Read Ashley's full article in Undark Magazine here.

Questions or ideas for future episodes? Email us at [email protected].

Learn more about sponsor message choices: podcastchoices.com/adchoices

NPR Privacy Policy

Transcript

Click on a timestamp to play from that location

0:00.0

This message comes from NPR sponsor Morgan Stanley with their podcast,

0:04.0

What Should I Do With My Money?

0:06.0

Smart people don't always feel smart about money.

0:08.0

Listen to What Should I Do With My Money to hear real people getting real help

0:12.0

from experienced financial advisors.

0:15.0

You're listening to Shortwave from NPR.

0:20.0

In 1990, the Department of Energy and the National Institutes of Health

0:25.0

launched a massive undertaking called the Human Genome Project.

0:30.0

People in the biology community and the genetics community refer to it as a moon shot for biology, if you will,

0:36.8

kind of on par with the Apollo mission.

0:38.9

Because for the first time ever, scientists were going to sequence the human genome as fully as possible.

0:45.6

That is, they were going to read all of the DNA from a person that kind of makes us a person.

0:51.5

Ashley Smart is a senior editor at Undark magazine where he recently wrote about this

0:56.1

landmark effort.

0:57.9

Genetic sequencing and testing may be widely available nowadays.

1:01.6

But back then it was something wildly unprecedented and

1:05.2

something hugely ambitious. Which is why the Human Genome Project took several

1:09.9

scientific teams over a decade and three billion dollars to complete.

1:15.2

But there's one part of the legacy that Ashley believes doesn't get talked about enough.

1:20.2

And that is the donors.

1:22.1

To sequence human DNA, you need actual DNA from humans.

1:27.0

And so one of the questions that people have been asking

...

Please login to see the full transcript.

Disclaimer: The podcast and artwork embedded on this page are from NPR, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of NPR and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright Β© Tapesearch 2025.