4.8 • 3.6K Ratings
🗓️ 21 November 2024
⏱️ 13 minutes
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0:00.0 | If you're anything like me, you have lots of ambitious plans for the future. |
0:06.0 | I've got a whole series of new books I want to write thousands more videos to script, |
0:11.0 | but guess what? |
0:13.0 | None of us may be able to do any of the things we want to do if we don't have our health. |
0:19.0 | Welcome to the Nutrition Facts podcast. I'm your host, Dr. Michael |
0:23.6 | Greger. Today we take a look at AMPK, a fascinating enzyme that acts as sort of our body's fuel |
0:31.0 | gauge. |
0:32.0 | In my book on everything evidence-based in weight loss, How Not to Diet, I had a section |
0:36.9 | entitled Amping A&PK. |
0:39.5 | AMPK is an enzyme that acts as a universal fuel gauge for plants and animals |
0:44.4 | revving up when it detects depletion of the universal fuel. |
0:49.2 | The universal energy currency in all of biology |
0:53.1 | is a molecule called adenosine triphosphate, commonly known as |
0:56.8 | ATP. The tri-in-trophosphate means three as in tricycle, or in this case, ATPs 3 |
1:03.3 | phosphates, where energy is stored. Plants make ATP with energy from the sun, and animals make it by |
1:09.8 | burning fat, carbohydrates, |
1:11.3 | and protein. |
1:12.7 | The energy is spent by releasing the phosphates, which transforms ATP to AMP, adenosine |
1:19.4 | mono-phosphate, with mono-meaning one, which then can be juiced up with two more phosphates |
1:24.5 | back to ATP, and the cycle continues. |
1:27.7 | In this way, every cell in our body and in every living thing is like a little rechargeable |
1:32.7 | battery. |
... |
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