The 5R Protocol That’s Helping People Reverse Disease Naturally

The Dr. Hyman Show

Dr. Mark Hyman

Health & Fitness, Nutrition, Medicine

4.6 • 8.7K Ratings

🗓️ 2 June 2025

⏱️ 59 minutes

🔗️ Recording | iTunes | RSS

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Summary

Many chronic health conditions—such as IBS, asthma, and autoimmune disorders—can be traced back to imbalances in the gut. Disruptions to the microbiome caused by antibiotics, poor diet, food sensitivities, and environmental exposures can lead to inflammation, malabsorption, and increased intestinal permeability (leaky gut). Addressing gut health through a structured Functional Medicine approach called the 5R’s of gut repair—removing harmful triggers, replacing missing digestive factors, reinoculating with beneficial bacteria, repairing the gut lining, and rebalancing lifestyle factors—can restore balance and improve systemic health. In this episode, I discuss, along with Dr. Elizabeth Boham and Raja Dhir, the Functional Medicine approach to healing the gut and why the gut is at the center of imbalances in the body, including many health conditions. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women’s Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. Raja Dhir is the co-founder and co-CEO of Seed Health, a microbiome science company developing innovative probiotics and living medicines to advance human and planetary health. He specializes in translating cutting-edge microbial research into impactful products and leads Seed Health’s academic collaborations with institutions such as MIT, Harvard, Stanford, Caltech, and the NIH. Raja co-chairs Seed’s Scientific Board alongside Dr. Jacques Ravel, guiding research across microbiology, immunology, genetics, and ecology. He also directs LUCA Biologics, a company focused on the vaginal microbiome and women's health, and oversees SeedLabs, which drives environmental initiatives. Through this work, Raja plays a key role in accelerating microbiome-based solutions from discovery to market. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: What Is Leaky Gut And How Can You Treat It?How to Select a Probiotic and the Future of the MicrobiomeHow To Do The 10-Day Detox

Transcript

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0:00.0	Coming up on this episode of the Dr. Hyman Show.
0:02.5	When you have the wrong bacteria and the wrong yeast levels,
0:06.0	you can get a lot of bloating after you eat,
0:08.0	you can get a lot of fatigue after you eat,
0:10.0	you can get those symptoms of constipation and diarrhea,
0:12.0	and that causes this inflammation in the digestive system,
0:16.0	so all of your digestive enzymes don't work well.
0:21.5	When I was just starting my medical journey as an emergency room physician, magnesium was a critical
0:25.9	element of our care.
0:26.9	We used it to treat all kinds of conditions, from arrhythmia to constipation to preeclampsia.
0:31.9	It turns out that magnesium is critically important outside of the emergency room, too.
0:35.8	In fact, it's one of the most important
0:37.6	minerals for all aspects of health. It participates in over 300 different biochemical reactions in
0:42.5	your body, yet over 60% of the population doesn't get the amount of magnesium they need from their
0:47.1	diet alone. That's why I'm such a big advocate of bioptimizers. Their magnesium breakthrough
0:51.6	supplement is the only supplement on the market that offers the full spectrum of all seven types of magnesium, specially formulated to reach every tissue in
0:58.9	your body to provide maximum health benefits. This height. Bioptimizers is offering my community 10% off.
1:04.8	Just head over to bioptimizers.com slash hymen with code hymen 10. That's bioptimizers.com slash hymen with code hymen 10 at checkout.
1:13.9	Now before we jump into today's episode, I'd like to note that while I wish I could help
1:17.9	everyone by my personal practice, there's simply not enough time for me to do this at scale.
1:22.2	And that's why I've been busy building several passion projects to help you better understand,
1:26.2	well, you. If you're looking for data about your biology, check out function health for real-time lab insights.
	...

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