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Short Wave

That Revolutionary Gene-Editing Experiment? So Far So Good.

Short Wave

NPR

Daily News, Nature, Life Sciences, Astronomy, Science, News

4.76K Ratings

🗓️ 20 November 2019

⏱️ 13 minutes

🧾️ Download transcript

Summary

Earlier this month NPR health correspondent Rob Stein introduced us to Victoria Gray, the woman at the center of a groundbreaking medical treatment using CRISPR, the gene-editing technique. This week, Rob reports exclusively for NPR on the first results of that closely-watched experiment. Follow host Maddie Sofia on Twitter @maddie_sofia. Email the show at [email protected].

Transcript

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0:00.0

You're listening to Shortwave from NPR.

0:05.0

Maddie's a fire here with NPR Health Correspondent Rob Stein, Rob.

0:08.6

Are you excited?

0:09.6

I am so excited.

0:11.4

Okay, so here's the deal.

0:13.6

This episode reveals the early first results of a groundbreaking medical experiment to treat

0:18.9

a woman named Victoria Gray.

0:21.0

Rob has been reporting on Victoria's journey exclusively for NPR and everything you're

0:25.4

about to hear makes a lot more sense if you hear our first episode about Victoria from

0:30.5

November 4th.

0:31.5

So if you miss that, go back and listen.

0:34.3

But Rob, for all the people, most of the people who are too impatient to go back to November

0:39.0

4th, set this up for me.

0:40.6

Okay, we're talking about Victoria Gray.

0:43.3

She's 34, she lives in Mississippi and she has four kids and she has sickle cell disease.

0:49.0

And that's an awful genetic condition where your red blood cells, you know, the ones that

0:52.6

carry oxygen.

0:53.6

Instead of being, you know, squishy and normal and healthy, they're sticky and misshapen

0:58.3

in this sickle shape, then it causes terrible pain.

1:01.7

And people with sickle cell, they often don't make it past their 40s.

1:04.9

It's a huge problem.

1:06.6

Something like 100,000 Americans of sickle cell and millions of people around the globe.

...

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