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Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Stimulant Laxatives Pharmacology

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

5716 Ratings

🗓️ 9 May 2019

⏱️ 14 minutes

🧾️ Download transcript

Summary

On this episode, I discuss the pharmacology of commonly used stimulant laxatives like sennosides and bisacodyl.



Stimulant laxatives "stimulate" the GI tract smooth muscle which helps propel fecal material out of the body and thus helping to relieve constipation.



Patients who are having diarrhea and are unsure of what medications they are taking should have their regimen assessed for these medications.



Chronic opioid therapy is a situation where chronic stimulant laxative therapy may be used.



Stimulant laxatives have very few drug interactions. However, bisacodyl effectiveness can be reduced by the use of antacids like calcium carbonate.

Transcript

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0:00.0

Hey all, welcome back to the real-life pharmacology podcast. I'm your host, Eric Christensen,

0:05.2

pharmacist. And today I'm going to cover stimulant laxatives. Now, as with any over-the-counter

0:13.9

product, there are a ton of different brand names and stimulant laxatives on the market.

0:21.2

So I obviously can't cover every single brand name that you might see out there.

0:26.7

However, there are two major drugs that are classified as stimulant laxatives.

0:34.0

And it is Bizzacotal, which is the generic name, and it is Sennicides or Sena is the other product common name.

0:43.9

Both these are stimulant laxatives.

0:47.7

Brand names you might see Sena, Sennacides,na cot uh... jerrycot xlax

0:56.5

uh... visicodal brand names you might see dulclax is definitely the most common

1:02.0

uh... i have seen

1:03.5

uh... various xlax products will have different ingredients in it depending upon

1:08.6

uh... what it's you know what's in it and what it is. So I can't stress that

1:13.9

enough. Obviously, hopefully, you're probably a healthcare professional listening to this.

1:19.6

You've really got to look at the back of that label if you absolutely want to know what's in

1:26.8

and over-the-counter product because these brand name

1:30.0

change.

1:31.4

There's different formulations and all that sort of stuff.

1:34.0

So pay attention, look at the back of the label.

1:37.3

If you're on a phone interacting with a patient, something like that, have them send you a picture,

1:42.9

have them read it off what it says on the back, which

1:47.0

that can be challenging sometimes too with visual difficulties and small writing, but do

1:52.5

the best you can to get the info off the back of the label rather than just the brand name

...

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