4.8 • 3.6K Ratings
🗓️ 18 November 2021
⏱️ 12 minutes
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0:00.0 | Trying to stay healthy can seem like a full-time job sometimes, especially during a pandemic. |
0:07.0 | But I'm here to make that goal a little easier. |
0:10.2 | Welcome to the Nutrition Facts Podcast. |
0:12.8 | I'm your host, Dr. Michael Greger. |
0:15.6 | Today, it's part two of our series on statins. |
0:19.6 | And we start with a Mayo Clinic visualization tool that will help you decide if cholesterol-lowering statin drugs are right for you. |
0:28.0 | Physicians have a duty to inform their patients about the risks and benefits of whatever they prescribe. |
0:33.6 | However, physicians rarely communicate the absolute risk numbers, such as numbers needed to treat. |
0:40.0 | In other words, how many people are actually helped by the drug? |
0:43.6 | Numbers needed to harm, in other words, how many people are actually hurt by the drug or prolongation of life? |
0:50.0 | How much longer will it enable you to live despite patients wanting all this information? |
0:56.8 | If doctors inform patients only about the relative risk reduction, for example, telling patients a pill will cut the risk of heart attacks by 34%. |
1:04.8 | 9 out of 10 agree to take it. |
1:06.8 | Give them the same information framed as absolute risk reduction, though. |
1:11.2 | 1.4% fewer patients had heart attacks. |
1:14.4 | And those agreeing to take the drug drops only 4 out of 10. |
1:17.6 | And use the numbers needed to treat, and only 3 in 10 patients would agree to take it. |
1:23.6 | So if you're a doctor, and you really want the patient to take the drug, which statistic are you going to use? |
1:30.4 | The use of relative risk stats to inflate the benefits and absolute risk stats to downplay any side effects has been referred to as statistical deception. |
1:41.2 | But you can see how easily you could manipulate people if you picked and chose how you were presenting the risk in benefits. |
1:48.2 | So ideally, you'd use both the relative risk reduction and absolute risk reduction stats. |
1:55.0 | In terms of benefits, when you compile a bunch of stat and trials together, it looks like the relative risk reduction is 25%. |
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