SNR #211: Brianna Stubbs, PhD - Ketogenesis, Metabolism and Ketone Ester Supplementation

Sigma Nutrition Radio

Danny Lennon

Sigma, Dietetics, Evidencebased, Nutrition, Training, Health & Fitness, Science, Diet, Fitness, Evidence, Bodybuilding, Health

4.8 • 626 Ratings

🗓️ 30 December 2017

⏱️ 62 minutes

🔗️ Recording | iTunes | RSS

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Summary

Brianna Stubbs, PhD

In 2016 Brianna completed her PhD in Metabolic Biochemistry at Oxford University. She also became a World Champion rower as part of the GB Rowing Lightweight Women's four person crew, and won 3 other World Rowing Championships medals. She has published peer-reviewed studies looking at ketone metabolism, ketone ester supplementation in athletes and effects of ketones on appetite.

In This Episode We Discuss:

Brianna's background as an elite-level rower
Her PhD research on ketone metabolism
Misconceptions about ketones (both endogenous and exogenous)
Ketogenesis: why do we make ketones?
Brianna's study examining effect of ketone ester supplementation on appetite and ghrelin levels
Who needs to even know their ketone concentration?
Ketone supplements: glycogen sparing or glycogen impairing?
Effect of ketone supplementation on fuel selection in endurance athletes
Potential for supplementation: where is the area we will most likely see some benefit?
Limitations of current literature base

Transcript

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0:00.0	Hello and welcome to another episode of Sigma Nutrition Radio.
0:27.0	As ever, I am your host, Danny Lennon.
0:29.2	And today we're at episode 211 of the podcast, our final episode of 2017.
0:36.7	And just before we get in a very special thank you to everyone who
0:40.1	has posted feedback about last week's episode, our special open conversation between Professor
0:46.4	Tim Noakes and Martin MacDonald on carbohydrate intake, insulin resistance and body fat regulation.
0:52.3	Lots of interest from you guys, plenty of people discussing it
0:56.5	and posting their thoughts. So thank you for that. Thank you for the interest. And maybe for any of you
1:00.9	who did not hear that episode yet, then it might be one to go click into your app and Mark to listen
1:06.1	later. That's episode 210 of the podcast, Professor Tim Noakes and Martin MacDonald.
1:12.6	So on to today's show, and I'm going to be talking with researcher Brianna Stubbs,
1:20.7	who has published peer review research on ketone metabolism and ketone ester supplementation.
1:27.4	She completed her PhD in metabolic biochemistry over at Oxford University in the UK and was
1:33.7	part of the group there that has published a number of peer-reviewed studies looking particularly
1:38.1	at ketone esters and how they can be used both in effects for athletic populations, so effect on endurance, sport,
1:46.1	performance and recovery, as well as their effect on things like appetite and ghrelin levels,
1:51.2	which Brianna has been the lead author on a couple of those studies, and we're going to talk
1:55.3	about those specifically today.
1:57.3	If you haven't heard our previous episode, episode 195 of the podcast with Dr. Brendan Egan of
2:04.6	Dublin City University, in that episode we talked about exogenous ketone supplementation as it
2:10.0	relates to sports performance. And a lot of the material there would be a nice adjunct to what
2:14.8	we're going to discuss today. So again, if you haven't listened
	...

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