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The People's Pharmacy

Show 1445: Your Brain on Pain: Why Chronic Pain Changes Everything

The People's Pharmacy

Joe and Terry Graedon

Health & Fitness, Medicine, Kids & Family, Alternative Health

4.5934 Ratings

🗓️ 18 September 2025

⏱️ 71 minutes

🧾️ Download transcript

Summary

The statistics are shocking. At any given time, nearly one fourth of American adults are experiencing low back pain. Even worse, roughly one-third of the population will have to deal with chronic pain at some point in their lives. How does the brain react to pain? What can people with chronic pain do to alleviate […]

Transcript

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0:00.0

I'm Joe Graydon.

0:01.5

And I'm Terry Graydon.

0:03.0

Welcome to this podcast of the People's Pharmacy.

0:06.1

You can find previous podcasts and more information on a range of health topics at

0:11.5

People's Pharmacy.com.

0:14.8

The CDC estimates that almost one in four American adults suffers chronic pain.

0:22.7

Are there successful treatment strategies? This is the People's Pharmacy with Terry and Joe Graydon.

0:31.6

The experience of pain is deeply personal.

0:40.4

Shouldn't treatment strategies be personalized as well?

0:44.1

What works for one person might not help someone else. We're honored to be speaking with one of the country's leading pain experts.

0:48.9

Dr. Sean Mackie is chief of Sanford's Division of Pain Medicine.

0:54.0

Dr. Mackey will offer insights into the multimodal approaches his patients have found helpful.

0:59.7

Coming up on the people's pharmacy, your brain on pain, why chronic pain changes everything.

1:14.2

In the People's Pharmacy Health Headlines, Daylight Savings Time will come to an end on November 2,

1:21.3

but scientists don't agree on the health implications of turning the clocks back an hour.

1:32.3

A Stanford University study published in the proceedings of the National Academy of Sciences suggests that going back and forth between standard time and daylight savings time

1:38.2

disrupts circadian rhythms.

1:41.2

The researchers found evidence that this increases the risk for obesity and stroke.

1:46.2

They calculated that sticking with standard time year-round would prevent 300,000 strokes each

1:53.3

year and cut down on obesity. People who usually stay up late suffer greater biological consequences

2:00.0

from shifts in time regimens.

2:02.2

Previous research blamed changing clocks for higher rates of car crashes and heart attacks.

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