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Science Friday

Scientists Are Uncovering A World Of ‘Dark Matter’ Carcinogens

Science Friday

Science Friday and WNYC Studios

Life Sciences, Wnyc, Science, Earth Sciences, Natural Sciences, Friday

4.55.5K Ratings

🗓️ 5 February 2024

⏱️ 18 minutes

🧾️ Download transcript

Summary

New findings about how substances like air pollutants can trigger cancer may help reveal carcinogens we were unaware of.

Transcript

Click on a timestamp to play from that location

0:00.0

Are we surrounded by carcinogens that awaken sleeper cancer cells in our bodies?

0:07.6

Air pollution itself is an enormous carcinogenic burden.

0:11.6

The number of exposed people is so large that the stakes become

0:14.8

enormous. It's Monday, February 5th and right again, it's Science Friday.

0:19.6

I'm Sci-Fi producer D Peter Schmidt.

0:25.0

Cancer is the result of DNA mutations that cause cells to grow out of control and develop

0:30.6

tumors.

0:31.6

And over the years, scientists have identified certain chemicals

0:33.9

called carcinogens that are directly linked to those cancer-causing

0:37.4

mutations like those found in cigarettes. But the rates of some cancers are

0:41.7

rising dramatically in certain populations,

0:44.4

leaving scientists to wonder what carcinogens they might be missing

0:47.9

and how traditional models of detecting them are falling short.

0:51.2

Ira Fleto talks to a cancer researcher to understand how scientists are rethinking their approach

0:56.6

to identifying carcinogens, what role air pollution plays, and why he's hopeful for the future of cancer

1:02.3

research.

1:04.0

My next guest is Dr. Siddhartha Mukruji,

1:07.0

author of the Pulitzer Prize winning book,

1:09.0

The Emperor of All Maladies, the biography of cancer. he recently wrote an article in the New Yorker

1:15.2

entitled all the carcinogens we can't see we routinely test for chemicals that cause mutations

1:21.9

what about the dark matter of carcinogens?

1:25.0

Substances that don't create cancer cells, but rouse them from their slumber.

...

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