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Finding Genius Podcast

Saving Lives in 3D – Lorenzo Moroni, Professor of Biofabrication, Regenerative Medicine, Maastricht University – Boundless Biofabrication: Advances in Drug Therapy and What the Future Holds for Regenerative Medicine

Finding Genius Podcast

Richard Jacobs

Medicine, Health & Fitness

4.41K Ratings

🗓️ 28 June 2018

⏱️ 23 minutes

🧾️ Download transcript

Summary

Kidney failure? No problem. Need a new heart? Check, working on it. Let's just head on over to the 3D printer and print one up and send you on your way. While this sounds like science fiction, and currently still is, the advances in biofabrication and 3D bioprinting may intersect in a jaw-dropping, historical moment some day in our future. To learn more about the stunning advances in medical biofabrication that are being put to work today, listen to Dr. Lorenzo Moroni's intensive discussion of the present and future of modern medical science.


Lorenzo Moroni, a professor of biofabrication for regenerative medicine at Maastricht University delivers a dense foundation of information on the advances in biofabrication models, and how they may open the door to medical breakthroughs in drug therapy. Specifically, biofabrication is the production of intricate living as well as non-living biological entities from natural biological materials such as living cells and biochemical molecules, etc.


Moroni holds a master's degree in biomedical engineering from Polytechnic University of Milan, Italy, and in nanoscale sciences at Chalmers Technical University, Sweden, as well as a Ph.D. cum laude from the University of Twente.


Moroni's lab works to originate medical applications toward the creation of biological models to test treatments for new drugs, and to gain a better understanding of the mechanisms behind the pathology of diseases in three dimensions.


The biomedical engineer details how biofabrication offers a more physiological, three-dimensional environment of a targeted tissue area or organ where the testing of new treatments and drugs is focused. Further, Dr. Moroni explains how testing drugs on cells of a three-dimensional substrate also enables higher quality testing of the efficacy and potency for these new drugs, chemical compounds, and therapies. As our bodies are three-dimensional, the testing of new drugs and therapies in three dimensions is more efficient, and provides better results than the traditional methods utilized in a two-dimensional laboratory cell culture testing environment.


Moroni discusses how biofabrication and 3D scaffolding allows for more targeted study and development of treatments and therapies for conditions or diseases that affect cartilage, heart valves, vascular tissue, and beyond. He touches on how these 3D processes are paving the way for a possible future that could see bioprinting of organs come to fruition, but cautions that we are still a long way away from reaching that monumental moment in history.

Transcript

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0:00.0

Welcome to Almost Here, Around the Corner of Future Technology Podcasts with Richard Jacobs.

0:07.0

Future Technologies

0:08.0

Boys to transform our lives for better or worse are the focus of this podcast. Almost here means these

0:14.8

technologies are now here and starting to be used or just around the corner for

0:19.6

Bitcoin to artificial intelligence, 3D printing, blockchain, virtual reality, and more.

0:25.0

Hello, this is Richard Jacobs with the Future Check Podcast.

0:30.0

My guest is Lorenzo Moroni.

0:32.0

He is professor of

0:33.2

biofabrication at Maestricht University in Holland. So Lorenzo, how you

0:37.7

doing?

0:38.7

I'm fine, my pitch. Yeah, thank you for coming. So tell me about your work, your research, how did you get interested in it and what is the research look like today?

0:49.0

Sure. Well, our research actually here here at Master University focuses around

0:53.7

biofabrication and we try to apply this interdisciplinary field towards

1:00.6

regenerative medicine applications or towards the creation of biological models that can be used to test new treatments or new drugs and understand possible pathological mechanism

1:18.5

behind certain diseases in three dimensions. And I'll explain a little bit later why three dimensions are more important than two dimensions.

1:30.0

I'm a biomedical engineer by training.

1:33.0

I graduated in fact actually I hold two master degrees in

1:37.0

in biomedical engineering at Polytechnic of Milan University

1:41.8

back home in Italy where I'm originally from and a second master in nanoscale

1:47.0

science and engineering from Charnurs University of

1:55.0

the University in Sweden and have got my PhD degree at 20 University

1:58.0

also in the Netherlands on biomaterials and additive manufacturing technologies or in general, careful fabrication technologies for tissue engineering and regenerative medicine applications.

...

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