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The John Batchelor Show

S8 Ep898: Henry Miller describes a "tour de force" at MIT where AI is used to discover new molecules to fight antibiotic resistance. This technology identifies structures that kill pathogens like staphylococcus and gonorrhea. (14/16)

The John Batchelor Show

John Batchelor

Society & Culture, Arts, News, Books

4.52.8K Ratings

🗓️ 20 May 2026

⏱️ 7 minutes

🧾️ Download transcript

Summary

Henry Miller describes a "tour de force" at MIT where AI is used to discover new molecules to fight antibiotic resistance. This technology identifies structures that kill pathogens like staphylococcus and gonorrhea. (14/16)
1750

Transcript

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0:00.0

I'm John Bachelor, and I'm speaking to Dr. Henry Miller, a physician.

0:20.0

We turn from the FDA to another three-letter institution, MIT.

0:26.4

And Henry, I work with AI all the time.

0:28.9

I have Claudette in full conversation about history,

0:33.4

and Claudette also does a wonderful job of formatting my documents.

0:37.2

At the same time, I'm reading

0:39.2

in Science Magazine and Nature magazine that AI has surprising value for scientific endeavor and for

0:46.9

thoroughness. I learn now that AI is being used by researchers at MIT to search out a problem I've always heard about, which is

0:57.2

that the abuse of antibiotics, that is, you don't take your full course of antibiotics, you're supposed

1:04.4

to take it for 10 days and you take it for three, you feel better, and you just lose the pills.

1:08.6

That that is increasingly a threat if you're in a hospital,

1:11.9

for example, with afflictions that can't be solved by antibiotics. Have I said that correctly,

1:17.5

doctor? Yes, John. You have. But as you intamated, antibiotic resistance is a huge and

1:27.0

increasing public health problem.

1:30.0

We haven't had a new class of antibiotics developed for half a century.

1:36.8

Darwinian evolution being what it is, survival of the fittest, bacteria that have mutations that enable them to resist the

1:47.7

available antibiotics proliferate and become useless. And we're seeing that more and more.

1:54.8

In fact, many of your listeners may have had the experience of a skin infection with

1:59.8

Staphylococcus or some sort of pneumonia or other

2:07.1

respiratory infection where antibiotics were first tried, didn't succeed, and their physicians had to go

2:15.0

to a second line antibiotic, which might not be as effective normally

2:19.9

or which has greater side effects. So we desperately need new antibiotics and new approaches.

...

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