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ZOE Science & Nutrition

Recap: Is the new obesity medication too good to be true? | Dr. Louis J Aronne

ZOE Science & Nutrition

ZOE

Nutrition, Health & Fitness, Education, Science

4.64.9K Ratings

🗓️ 1 July 2025

⏱️ 15 minutes

🧾️ Download transcript

Summary

Today we’re talking about obesity medication. Did you know that over 200 illnesses are linked to unhealthy weight gain? It's no surprise that combatting obesity has become a major focus of modern medical research. In recent years, this research has led to a new generation of weight-loss medications that are delivering dramatic results. But are these drugs truly revolutionary or just too good to be true? One thing is certain - people have a lot of questions. Today, I’m joined by Dr. Lou Aronne to help us separate the hype from the hard facts. 🥑 Make smarter food choices. Become a member a zoe.com - 10% off with code PODCAST 🌱 Try our new plant based wholefood supplement - Daily30+ *Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system 📚 Books from our ZOE Scientists: The Food For Life Cookbook by Prof. Tim Spector Food For Life by Prof. Tim Spector Every Body Should Know This by Dr Federica Amati Free resources from ZOE: Live Healthier: Top 10 Tips From ZOE Science & Nutrition  Gut Guide - for a healthier microbiome in weeks Have feedback or a topic you'd like us to cover? Let us know here Listen to the full episode here

Transcript

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0:00.0

Hello and welcome to Zoe Recap, where each week we find the best bits from one of our podcast episodes to help you improve your health.

0:09.0

Today we're talking about resistance training. When we think of exercising in our 70s and 80s, we often focus on gentle activities like walking, swimming some lengths in a pool.

0:20.0

However, are we overlooking a crucial

0:22.4

part of the fitness puzzle, something that could truly transform our later years. Strength training.

0:29.1

Because as we age, muscle loss isn't just about losing tone, it's about losing independence.

0:34.9

Dr. Brad Schoenfeld joins me to share how resistance training can preserve

0:38.4

strength, improve ability, and support a long and active life. Whether you've got five minutes

0:44.1

or 50, he'll show you how to get started. No gym membership required.

0:51.2

When muscles begin to shrink and they get weaker, you do not have sufficient strength to carry out basic tasks.

0:58.7

And then you lose your functional independence, which is the primary reason that most people go into nursing homes to care facilities as they age.

1:08.1

It also can lead to falls, hip fractures, which often are fatal over time,

1:15.5

that mortality in those elderly individuals who undergo falls is close to 50% over a period of a

1:22.5

couple of years. The functional disabilities, of course, are far-reaching as far as people's ability to carry out

1:30.4

activities on their own, which not only is really bad as far as their ability to engage in life,

1:38.7

but it's also demoralizing mentally. There's aspects far beyond that that also are important.

1:46.0

Muscles store glucose.

1:53.9

So glucose, of course, is stored in muscles as glycogen. If your muscles start to shrink,

2:05.3

you have less ability to store glucose. That tends to lead to diabetes. Also the functionality of the muscle themselves in terms of their insulin receptors, their ability to get glucose into the muscles. So it's not just the size and their

2:09.7

ability to store a certain amount of glucose, but it's their ability to take in the glucose.

2:14.9

And by the way, you mentioned earlier, also by pulling on the bones, they help to strengthen

2:19.2

bones or when they weaken, they facilitate the decrease in bone density.

2:24.8

So there's just really all organ systems kind of can be affected by muscle.

...

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