Pulmonary Embolism - Part 4
Hospital and Internal Medicine Podcast
Gil Porat, M.D., FACP, CPT
4.7 • 587 Ratings
🗓️ 10 October 2016
⏱️ 24 minutes
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Summary
Transcript
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| 0:00.0 | There's no end to topics and tangents that we could go off on with pulmonary embolism, |
| 0:06.0 | but I do want to cover a few more things before we close out pulmonary embolism and move on to different lectures. |
| 0:13.0 | And one of the things that is still overused in the treatment, and I hate to use the word treatment, |
| 0:18.1 | because it's not really a treatment, but one of the things that's overused is inferior venicava filters. |
| 0:25.6 | Both the American and the European guidelines do not recommend routine use of IVC filters in patients with acute pulmonary embolism. |
| 0:38.3 | If you can be treated with anticoagulants, meaning if you're able to start anticoagulation, |
| 0:45.3 | is there a benefit to adding an IBC filter? |
| 0:50.3 | So let's look at the evidence on this for a minute. |
| 0:52.3 | So there were two trials that often get quoted. |
| 0:55.8 | One is the first preptic trial. |
| 0:58.1 | So that's P-R-E-P-I-C, and that was in circulation in 2005 in July that year. |
| 1:04.4 | And that was an eight-year follow-up of patients with permanent Venicava filters in the prevention of pulmonary embolism. |
| 1:12.1 | It was called the PEPT trial because the title of it is Prevention to the Risk |
| 1:16.7 | to Embolai Pomeronear Interruption Cave. |
| 1:20.5 | I can't really do a French accent. |
| 1:22.0 | But anyway, that's what it was called. |
| 1:24.2 | So at eight years, they looked at these patients and didn't help survival. |
| 1:29.3 | Actually, it had no effect on survival if you put in one of these permanent IVC filters in this randomized trial. |
| 1:37.4 | So the thing they also looked at is deep pain thrombosis, and probably not surprising if you put in a foreign thing like an iBC |
| 1:47.0 | filter it actually increased the dvt rate now it should be noted that the number of pulmonary |
| 1:55.7 | embolisms actually did decrease in those that got the IBC filter. |
| 2:01.4 | But again, just because you got the filter and decreased the rate of pulmonary embolisms, |
... |
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