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This is Scientific Americans' 60-second science. I'm Steve Merski.

We focus on what is called recurrent obesity or yo-yo obesity, which is a feature which affects close to 80% of all overweight individuals worldwide.

Iran Elinov of the Whiteman Institute of Science in Israel.

This is the phenomenon in which we gain weight and then we go on a

successful diet, but within 12 months we go back to our original weight and we even gain more

weight from cycle to cycle. So this is called recurrent obesity. But Elinoff may have taken a step

toward getting a handle on that frustrating post-diet pound packing that leaves people heavier than when they started.

He spoke February 17th at the annual meeting

of the American Association for the Advancement of Science in Boston.

We developed a few models in mice,

which feature this exact pattern of recurrent,

exaggerated obesity following cycles of obesity and successful dieting.

And what we found was that the one important determinant which drives this exaggerated weight

regent tendency is a persistent alteration of the composition and function of our gut microbiome

following a successful dieting.

In other words, we diet and we normalize all of our gut microbiome following a successful dieting. In other words,

...