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Science Friday

Paralysis Treatment, Protein Vaccines Advantages, How Cuba Made Five Vaccines, Fish Sounds. Feb 18, 2022, Part 2

Science Friday

Science Friday and WNYC Studios

Life Sciences, Wnyc, Science, Friday, Natural Sciences

4.46.3K Ratings

🗓️ 18 February 2022

⏱️ 48 minutes

🧾️ Download transcript

Summary

New Device Helps People With Paralysis Walk Again Spinal cord injuries are notoriously difficult to treat, especially for those who have been paralyzed for several years. Now, researchers have developed a new implant that is able to reverse paralysis in patients with complete spinal cord injuries. The device uses specially designed electrodes, which bring the brain back into communication with the patient’s lower body. The findings were recently published in the academic journal Nature Medicine. Ira talks with the study’s co-authors, Jocelyne Bloch, a neurosurgeon at Lausanne University Hospital, and Grégoire Courtine, professor of neuroscience at the Swiss Federal Institute of Technology, based in Lausanne, Switzerland.   Could Protein-Based Vaccines Help Close The Global Vaccination Gap? A new generation of COVID-19 vaccines are being developed and distributed around the world. They’re called recombinant-protein vaccines. But the tech is actually not at all new. In fact, It’s been used to produce hepatitis C and pertussis vaccines for decades. These protein-based vaccines have an edge over mRNA vaccines in a few ways. They’re just as effective, cheaper and simpler to manufacture, and easier to distribute. So why, two years into the pandemic, have they just started gaining traction? And can recombinant-protein vaccines help close the global coronavirus vaccination gap? Ira discusses these developments with Dr. Maria Elena Bottazzi, the co-creator of Corbevax, a patent-free protein-based vaccine, for which she was recently nominated for the Nobel Peace Prize. She’s also the co-director of the Center for Vaccine Development at Texas Children’s Hospital, and a professor at the Baylor College of Medicine, based in Houston, Texas.   How Cuba Developed Five COVID-19 Vaccines Cuba was able to quickly produce five coronavirus vaccines, thanks to the island’s robust biotech industry. For decades, Cuba has produced its own home-grown vaccines and distributed them to neighboring countries. But sanctions and political dynamics have complicated Cuba’s ability to distribute their COVID-19 vaccines with the world. Ira talks with Helen Yaffe, senior lecturer of economic and social history at Glasgow University, and author of We Are Cuba! How a Revolutionary People Have Survived in a Post-Soviet World.   Fish Make More Noise Than You Think One of the most famous films of undersea explorer Jacques Cousteau was titled The Silent World. But when you actually stop and listen to the fishes, the world beneath the waves is a surprisingly noisy place. In a recent study published in the journal Ichthyology & Herpetology, researchers report that as many of two-thirds of the ray-finned fish families either are known to make sounds, or at least have the physical capability to do so. Some fish use specialized muscles around their buoyancy-modulating swim bladders to make noise. Others might blow bubbles out their mouths, or, in the case of herring, out their rear ends, producing “fish farts.” Still other species use ridges on their bodies to make noises similar to the way crickets do, grind their teeth, or snap a tendon to sound off. The noises serve a variety of purposes, from calling for a mate to warning off an adversary. Aaron Rice, principal ecologist in the K. Lisa Yang Center for Conservation Bioacoustics at the Cornell Lab of Ornithology in Ithaca, walks Ira through some of the unusual sounds produced by known fish around the world—and some mystery noises that they know are produced by fish, but have yet to identify.

Transcript

Click on a timestamp to play from that location

0:00.0

This is Science Friday. I'm Iroflato. Spinal cord injuries are notoriously difficult to treat,

0:06.7

especially for those who have been paralyzed for several years. But now researchers have developed a new

0:11.9

implant that is able to reverse paralysis in patients with complete spinal cord injuries. It uses

0:19.3

specially designed electrodes which can bring the brain

0:23.0

back into communication with the patient's lower body. The findings were published in the journal

0:28.1

Nature Medicine. Joining me now to talk more about this exciting new development are the study's

0:33.3

co-authors. Jocelyn Block, neurosurgeon at Lausanne University Hospital, and Greg Gouard Cortin,

0:40.7

Professor of Neuroscience at the Swiss Federal Institute of Technology based in Lausanne, Switzerland.

0:46.7

Welcome to Science Friday.

0:48.5

Thank you very much.

0:49.8

Thank you.

0:51.0

Dr. Block, tell me me how does this implant work?

0:55.0

So I implant electrodes and these electrodes are located just upon the spinal cord

1:04.0

and they are linked to a neurostimulator that is a little computer like a pacemaker that

1:08.5

is located in the region of the abdomen in the belly

1:12.3

and connected to the electrodes. So how does it work? So we put programs on this little computer

1:19.0

and we studied how to mimic the activation of the spinal cord in reality and physiologically.

1:26.5

And we do exactly the same with the electricity.

1:30.1

So it means that when you walk, you generally flex your hip and then do extension and flexions

1:38.9

on the right, on the left, and we activate the different parts of the spinal cord that are responsible for

1:46.3

this or this function. And once the stimulation is started, the patient is able to control his

1:52.8

legs at will. As soon as we start understanding what to stimulate, so it takes a few hours to

...

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