4.6 • 732 Ratings
🗓️ 18 September 2025
⏱️ 19 minutes
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| 0:00.0 | Welcome to another edition of Cool Stuff Ride Home. On today's episode, elderly cats with dementia may hold clues for Alzheimer's disease in humans. |
| 0:15.0 | Plus, people with ADHD, well, they may have an underappreciated advantage, and it's called hyper curiosity. |
| 0:22.3 | Details on the way. |
| 0:23.9 | That plus a look at this day in history coming up, it's cool stuff. |
| 0:27.8 | And now a story from Science News and author Claudia Lopez Laredo. |
| 0:32.3 | As cats age, they may yowl more than usual at night, have trouble sleeping, or sleep too much, and act |
| 0:38.5 | generally confused or disoriented. Now, a new study shows that, just like in humans with |
| 0:44.1 | Alzheimer's disease, amyloid beta plaques build up in the brains of aging felines and may contribute |
| 0:50.8 | to dementia-like behaviors. In cats, that buildup could be causing a cascade of |
| 0:56.3 | problems within the brain, such as hyperactivation of immune and other supporting brain cells |
| 1:01.4 | that attack the synapses that connect nerve cells. Researchers reported that back on August 11th |
| 1:07.1 | in the journal, European Journal of Neuroscience. Aged cats with and without dementia had |
| 1:12.9 | similar features and only a small number of cats were studied. But these findings could start |
| 1:18.3 | helping researchers better understand how cats age and potentially develop treatments for feline |
| 1:24.1 | dementia as well as provide new insights into how the disease progresses in humans. |
| 1:29.5 | Earlier studies had found amyloid beta in the brains of cats, but scientists didn't know to what |
| 1:34.8 | extent it was disrupting brain function. Robert McGeachin, a veterinarian at the University of |
| 1:40.4 | Edenberg, knew that the number of synapses decreased early in Alzheimer's disease in humans. |
| 1:46.3 | And so he and his team decided to focus on these connections in their cat study. |
| 1:50.4 | They looked at the post-mortem brains of seven young cats and 18 older ones, |
| 1:55.8 | including eight with behavioral signs of dementia. |
| 1:58.9 | Using fluorescent markers that find and cling to amyloid beta, |
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