Every supermarket has a premium range, but there's only one number one from Waitrose,

with products like the number one Wagyu Topside seasoned roasting joint, naturally marbled and meltingly tender.

Or the number one sticky cinnamon bun pudding?

Buttery, rich and perfectly spiced.

And the number one smoked silver fox cheddar, 18-month matured, oaky and creamy.

Food worth getting the fancy plates out for. Waitrose, the home of food lovers. Selected stores

subject to availability. Happy Monday, listeners.

For Scientific American Science Quickly, I'm Rachel Thaltman.

You're listening to our weekly science news roundup.

First, let's take a quick tour through last week's Nobel Prize winners.

Last Monday, the 2025 Nobel Prize in Physiology or Medicine went to Mary E. Brunco, Fred

Ramsdale, and Shimon Sakaguchi for discovering how the body stops the immune system from

attacking itself. The immune system normally fights off infections and diseases, but in conditions like rheumatoid

arthritis or type 1 diabetes, it mistakenly targets the body's own tissues.

The laureate's research focuses on the type of so-called T-cells that act as internal regulators,

keeping this friendly fire in check.

During the 1990s, Sakaguchi found that mouse immune cells bearing a particular protein

marker were essential for preventing self-attack.

Eliminating these cells led to widespread tissue damage.

Several years later, Brunco and Ramsdell identified the genetic switch behind these regulatory

cells while studying mice with severe autoimmune disorders. Their findings have inspired

more than 200 clinical trials exploring therapies that include new ways to treat autoimmune

...