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🗓️ 9 October 2014
⏱️ 29 minutes
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Nobel Prizes 2014 The annual Nobel Prizes for Physiology or Medicine, Physics and Chemistry were announced this week.
The Nobel Prize for Physiology or Medicine has been awarded to UK-based researcher Prof John O'Keefe as well as May-Britt Moser and Edvard Moser who discovered the brain's "GPS system". They discovered how the brain knows where we are and is able to navigate from one place to another. Their findings may help to explain why Alzheimer's disease patients cannot recognise their surroundings.
The 2014 Nobel Prize for physics has been awarded to Professors Isamu Akasaki, Hiroshi Amano and Shuji Nakamura in Japan and the US, for the invention of blue light emitting diodes (LEDs). This enabled a new generation of bright, energy-efficient white lamps, as well as colour LED screens.
The 2014 Nobel Prize in Chemistry has been awarded to Eric Betzig, Stefan Hell and William Moerner for improving the resolution of optical microscopes. This type of microscope had previously been held back by the presumed limitation that obtaining a better resolution than half the wavelength of light would be impossible. But the laureates used fluorescence to extend the limits of the light microscope, allowing scientists to see things at much higher levels of resolution.
GAUGE The UK has a database for the amount of greenhouse gases we emit each year - usually measured in Gigatonnes of carbon. It's compiled by adding up emissions from various individual sources - be it a coal-fired power station or a wetland bog. This amount is used worldwide, but it is an estimate. A project called Greenhouse gas UK and Global Emissions, or GAUGE, is - for the first time - verifying these estimates by measuring what's in the atmosphere on a much larger scale.
Genetics and Diabetes Type 2 diabetes is globally the fastest growing chronic disease. The World Health Organisation estimates more than 300 million people are currently afflicted, rising to more than half a billion by 2030. It might seem on the surface to be a disease with a simple cause - eat too much & exercise too little - and the basic foundation is a relative lack of the hormone insulin. But as with most illnesses, it's much more complicated, not least because a large number of disease processes are happening all at once. In 2010, a particular gene variant was associated with around 40% of Type 2 diabetics - not directly causal, but this so-called 'risk variant' increases the chance of developing the condition if you have the wrong lifestyle. Research published in the journal Science Translational Medicine this week identifies a drug called yohimbine as a potential treatment to help Type 2 diabetics, one that targets this specific genetic make-up.
UK Fungus Day October 12th is UK Fungus Day, a chance for us to celebrate these cryptic, often microscopic, but essential organisms. Usually hidden away inside plants or in soil (or if you're unlucky, in between your toes), fungi have largely been growing below scientists' radars for centuries. Mycologists still don't know anything close to the true number of fungi that exist on the planet. About a hundred thousand have been formally identified, but it's estimated that anywhere from half a million to ten million species may exist. This dwarfs, by several orders of magnitude, how many mammals there are on Earth. And, increasingly, we're realising quite how crucial fungi are to the functioning of our ecosystems. Head of Mycology at The Royal Botanic Gardens Kew, Bryn Dentinger, explains how valuable fungi really are.
Producer: Fiona Roberts Assistant Producer: Jen Whyntie.
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| 0:29.1 | Hello you this is the podcast of BBC Inside Science first broadcast on the 9th of October. |
| 0:35.0 | Later on the show we'll be celebrating UK Fungus Day which is on Sunday |
| 0:39.0 | which is also the birthday of our producer Fiona Roberts, happy fee i'm adam rutherford terms and |
| 0:44.2 | conditions can be found at bibec.co dot uk slash radio four |
| 0:48.4 | a program crammed with exciting science this week we have a potential new drug treatment for type 2 diabetes |
| 0:54.9 | we have a technique for clocking greenhouse gas emissions and we have the biggest |
| 0:59.4 | party for mushrooms in the social calendar yes Yes, it's UK Fungus Day this Sunday. What do you mean |
| 1:05.3 | you don't have that in your diary? But first it's been Nobel Week, the annual jamboree that |
| 1:09.9 | lionizes scientists and celebrates science in equal measure. |
| 1:14.0 | Medicine and Physiology was announced on Monday, physics on Tuesday and chemistry on Wednesday. |
| 1:19.2 | And the dust is now settled. |
| 1:20.4 | Our Nobel expert Roland Peas is here in the studio to do the post-match analysis. |
| 1:25.0 | Three neuroscientists picked up the gong for medicine and physiology, Norwegian husband and wife, |
| 1:29.0 | team Edvard and my Brit Moza, and naturalised Brit John O'Keefe from University College London. |
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