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Pat Mayo Experience

NFL Week 6 DraftKings Picks 2025 | Best DFS NFL Lineups, Ownership Projections

Pat Mayo Experience

Mayo Media Network

Golf, Player Props, Nfl Picks, Sports Analysis, Nfl Betting, Underdog Nfl Picks, Underdog Fantasy, Football, Fantasy Football, Pga Tour Betting Picks, Daily Sports Podcast, Pga Golf Betting, Pga Fantasy Golf Tips, Pga Event Daily Preview, Same Game Parlay Picks, Golf Betting Picks, Golf Betting Insights, Nfl Betting Advice, Golf Betting, Golf Dfs Strategy, Pat Mayo Sports Betting, Nfl Betting Predictions, Draftkings Picks, Fantasy Sports, Sports

55.3K Ratings

🗓️ 10 October 2025

⏱️ 87 minutes

🧾️ Download transcript

Summary

Pat Mayo, Tyler Tamboline, and John Breslin of 4for4 DFS Fantasy break down the best 2025 NFL Week 6 DraftKings picks, lineups, and DFS strategy to help you build winning rosters. We cover ownership projections, game stacks, top plays, fades, and Underdog Pick’em picks for Week 6. Whether you’re entering GPPs or cash games, this guide has you covered.

Transcript

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0:00.0

Thank you.

0:01.5

The Pat Mayo Experience.

0:03.9

Pat Mayo Experience.

0:05.4

That's Mayo Experience.

0:08.2

Have you experienced.

0:11.7

Experience.

0:13.3

Welcome to the Pat Mayo Experience, presented by Underdog the Week 6, Draft King's Picks, Preview, lineup building, some ownership, some pivots.

0:22.6

The best way you can construct your lineups,

0:25.5

Tambo from Shipit Nation on the line from 4F4.com.

0:26.7

We got John Breslin.

0:29.5

Fellas, how was your week number five?

0:30.2

Was it profitable?

0:31.8

Because mine was, thanks to you guys.

0:34.1

So no.

0:39.6

Justin Fields, like, was so frustrating because I was way under the field on Justin Fields.

0:43.5

You know, he came in at like 30%, 40% in some single entry.

0:48.3

And my, my pivot that I liked was C.J. Stroud, just I didn't play enough C.J. Stroud.

0:50.0

I still had too much Justin Fields.

0:54.8

And then Fields ended up, like, getting there in the end, you know, in garbage time.

1:00.0

And, you know, elevated 30, 40% of the field above like my CJ Stroud lineup.

1:02.5

Yeah, I was on the other side of that, Tambo. You guys helped me build a just DAC onslaught with Breece Hall coming back the other way.

1:08.0

And that allowed, because that was so cheap, you know, you mix in some

...

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