News Flash Freeze: Inhalable Therapies Improve Drug Efficacy and Adverse Events Profiles
Finding Genius Podcast
Richard Jacobs
4.4 • 1K Ratings
🗓️ 11 July 2021
⏱️ 23 minutes
🧾️ Download transcript
Summary
Finally, you can take a deep breath in and relax…knowing you've also taken the lowest efficacious dose of your medicine, with less worry over adverse events. And it's all thanks to a company called TFF Pharmaceuticals.
Press play to learn:
- What specific problem TFF technology solves in terms of drug metabolism and systemic absorption
- How TFF technology can be applied to the area of vaccines
- Whether TFF technology could be used with cannabinoids as an alternative to vaping
Glenn Mattes has worked in the pharmaceutical industry for over forty years now, and for the past four years, has served as CEO of TFF Pharmaceuticals, a Thin Film Freezing technology platform that can improve the properties of drug formulation, delivery, and administration while maintaining efficacy and avoiding many adverse events associated with other drug therapies.
The Thin Film Freezing technology uses flash freezing to capture pharmaceutical drugs in a highly active state and convert them into highly concentrated powders. These powders can then be put into a capsule and inhaler device, allowing for administration directly into the lungs. Since the lung is an ideal organ for drug metabolism and distribution throughout the body, lower doses of the drug can be used to achieve the same or better efficacy with lower incidence of adverse events.
Other substances being formulated at TFF Pharmaceuticals can be inhaled through the nose, and in the works is a formulation that can be applied to the eyes or skin.
Mattes explains the science behind this technique, including the details of how and why it works, and the specific ways in which it can be applied.
Learn more at https://tffpharma.com/.
Episode also available on Apple Podcast: http://apple.co/30PvU9C
Transcript
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| 0:00.0 | Forget frequently asked questions. |
| 0:02.0 | Common sense, common knowledge, or Google. |
| 0:05.0 | How about advice from a real genius? |
| 0:07.0 | 95% of people in any profession are good enough to be qualified in license. |
| 0:11.0 | 5%? |
| 0:12.0 | Go above and beyond. |
| 0:13.0 | They become very good at what they do. |
| 0:15.0 | But only 0.1% are real geniuses. |
| 0:18.0 | Richard Jacobs has made his life's mission to find them for you. |
| 0:22.0 | He hunts down and interviews geniuses in every field. |
| 0:25.0 | Sleep science, cancer, stem cells, ketogenic diets, and more. |
| 0:29.0 | Come the geniuses. |
| 0:30.0 | This is the Finding Genius Podcast. |
| 0:33.0 | The Richard Jacobs. |
| 0:38.0 | Before we begin, a note from our sponsor. |
| 0:40.0 | I'm Richard Jacobs, executive director of the Nonprofit Finding Genius Foundation, and host |
| 0:45.0 | of the Finding Genius Podcast. |
| 0:46.0 | In late 2016, I was re-rendered at 65 miles an hour by a truck on the highway, which sent |
| 0:52.6 | me off-road into a ditch. |
| 0:54.8 | The impact of the collision gave me a concussion and other injuries. |
| 0:58.0 | At the hospital, a CT scan showed that I had thyroid nodules, which turned out to be cancer. |
| 1:03.0 | It was then, when I had a biopsy, my neck, that I realized, even if I was a million there, |
... |
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