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The Diary Of A CEO with Steven Bartlett

Most Replayed Moment: The Role of Dopamine in Addiction and Motivation - Anna Lembke

The Diary Of A CEO with Steven Bartlett

FlightStory

Society & Culture, Business, Education

4.613.2K Ratings

🗓️ 25 July 2025

⏱️ 25 minutes

🧾️ Download transcript

Summary

In today’s moment, renowned neuroscientist and author, Anna Lembke, explores the fascinating science of dopamine and its impact on our behaviour. Discover why dopamine is fundamental to survival, how it drives pleasure and motivation, and why we are more vulnerable to addiction than we think. Neuroscientist Anna Lembke is the author of bestselling book, Dopamine Nation. As a professor of psychiatry and the Medical Director of the Stanford Addiction Medicine program, she has become a leading expert on the brain’s reward system. Her work explores how the balance of pleasure and pain in the brain can lead to addiction and what happens when we overstimulate our reward pathways in the modern world. Listen to the full episode here! Spotify: https://g2ul0.app.link/QYBqCgLtgVb Apple: https://g2ul0.app.link/wiYqNPRtgVb Watch the episodes on YouTube: ⁠https://www.youtube.com/c/%20TheDiaryOfACEO/videos⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

I've rolled out uni because I want to live at home.

0:02.5

I've ruled out uni because I want to earn money.

0:05.7

I've ruled out uni because of my grades.

0:10.1

Study with the Open University and there's no need to rule out anything.

0:13.9

With our respected degrees, you can learn from home and work alongside study.

0:18.1

We're open to all. Plus, you'll have the support of expert tutors. So rethink your

0:23.6

future with the degree you didn't think was possible. The Open University. The future is open.

0:33.6

You wrote one of the most iconic, well-known books about dopamine, which propelled the subject matter of dopamine into the public consciousness.

0:42.3

But I guess the most important question I should ask you is, why does dopamine matter?

0:49.3

Ah, good question, good place to start.

0:53.0

I mean, dopamine matters because it's fundamental to our survival,

0:58.0

right? So it's the chemical that we make in our brain that tells us this is something we should

1:03.3

approach, explore, investigate. So it's really almost the survival chemical. So what is dopamine?

1:10.7

If you had to explain it to a 10-year-old, how would you go about explaining it?

1:14.6

So dopamine is a chemical that we make in our brain.

1:19.6

It has many different functions, but one of its most important functions is that it helps us

1:26.6

experience pleasure, reward, and motivation. It may

1:31.8

be even more important for the motivation to do things than it is for the pleasure itself.

1:37.9

So for example, there's a very famous experiment in which rats were engineered to have

1:43.3

no dopamine in the brain's reward pathway.

1:46.0

And the scientists discovered that if they put food in the rat's mouth, the rat would eat the food,

1:51.0

would seem to get some pleasure from the food, if you can determine that from watching a rat eat,

...

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