meta_pixel
Tapesearch Logo
Log in
TED Talks Daily

Math can help uncover cancer's secrets | Irina Kareva

TED Talks Daily

TED

Society & Culture, Ted, Ted Talks Daily, Ted Podcast, Ted Talks

4.112.1K Ratings

🗓️ 3 April 2018

⏱️ 8 minutes

🧾️ Download transcript

Summary

Irina Kareva translates biology into mathematics and vice versa. She writes mathematical models that describe the dynamics of cancer, with the goal of developing new drugs that target tumors. "The power and beauty of mathematical modeling lies in the fact that it makes you formalize, in a very rigorous way, what we think we know," Kareva says. "It can help guide us to where we should keep looking, and where there may be a dead end." It all comes down to asking the right question and translating it to the right equation, and back.



Hosted on Acast. See acast.com/privacy for more information.

Transcript

Click on a timestamp to play from that location

0:00.0

This TED Talk features mathematician Irina KRIVA, recorded live at TED-At-Mirk, K-G-A-Darmstadt, Germany, 2017.

0:10.6

I am a translator. I translate from biology into mathematics and vice versa. I write mathematical models,

0:19.6

which in my case are systems of differential equations,

0:21.6

to describe biological mechanisms such as cell growth.

0:25.6

Essentially, it works like this.

0:28.6

First, I identify the key elements that I believe may be driving behavior over time

0:33.6

of a particular mechanism.

0:35.6

Then I formulate assumptions about how these elements interact with each other

0:41.3

and with their environment.

0:43.3

It may look something like this.

0:45.3

Then I translate these assumptions into equations,

0:48.3

which may look something like this.

0:51.3

Finally, I analyze my equations and translate the results back into the language of biology.

0:58.2

A key aspect of mathematical modeling is that we, as modelers, do not think about what things are.

1:04.9

We think about what they do. We think about relationships between individuals, whether they be

1:10.1

cells, animals animals or people,

1:12.2

and how they interact with each other and with their environment.

1:15.9

Let me give you an example.

1:18.0

What do foxes and immune cells have in common?

1:23.0

They're both predators,

1:25.0

except foxes feed on rabbits

1:27.9

and immune cells feed on invaders, such as cancer cells.

...

Please login to see the full transcript.

Disclaimer: The podcast and artwork embedded on this page are from TED, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of TED and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright © Tapesearch 2026.