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Next Up with Mark Halperin

Marc Andreessen on AI and Tech Culture in 2025, Trump Era Myths Busted, Charlie Kirk's Faith Message

Next Up with Mark Halperin

MK Media

News, Daily News, Politics

4.61.2K Ratings

🗓️ 30 September 2025

⏱️ 54 minutes

🧾️ Download transcript

Summary

Mark Halperin opens today’s episode with a new reported monologue pushing back on the idea that American history began just ten years ago when Donald Trump went down the escalator, highlighting three current controversies with deep roots. He shows how lawfare, the decline of opportunity and purpose among young men, and government shutdown brinkmanship were all entrenched features of American politics and culture long before Trump entered the scene. By tracing their history back decades, Mark explains why these battles should not be seen as Trump-era phenomena, but as part of a much longer story in American life. Then, Mark sits down for a rare conversation with tech pioneer Marc Andreessen about where technology is heading. Andreessen explains why some people thrive with AI while others fall behind – and why it depends less on the tools you have than how you use them. He discusses China’s dangerous edge in AI and manufacturing, reflects on the culture that made Silicon Valley a global force, and hints at the breakthroughs that could redefine how we live, work, and compete in the years ahead. Stay tuned at the end of the episode for a special “Last Up,” featuring a message from Charlie Kirk on freedom, religion, and society – and why they are inseparable. Chapter: For free and unbiased Medicare help, dial 262-454-0503 or go to https://askchapter.org/mark Disclaimer: Chapter and its affiliates are not connected with or endorsed by any government entity or the federal Medicare program. Chapter Advisory, LLC represents Medicare Advantage HMO, PPO, and PFFS organizations and standalone prescription drug plans that have a Medicare contract. Enrollment depends on the plan’s contract renewal. While we have a database of every Medicare plan nationwide and can help you to search among all plans, we have contracts with many but not all plans. As a result, we do not offer every plan available in your area. Currently we represent 50 organizations which offer 18,160 products nationwide. We search and recommend all plans, even those we don't directly offer. You can contact a licensed Chapter agent to find out the number of products available in your specific area. Please contact Medicare.gov, 1-800-Medicare, or your local State Health Insurance Program (SHIP) to get information on all your options. Delta Rescue: Visit https://DeltaRescue.org to learn more

Transcript

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0:00.0

Welcome in, everybody. Thank you for being part of Next Up as a Nexter. We're honored to have you here,

0:07.3

first episode of the week and eager to have this episode roll an unfurl in front of your eyes and ears.

0:16.4

I'm Mark Kalprin, editor-in-chief of the interactive video platform 2-way and the host here for you,

0:21.8

your guide to everything next up to bring you my exclusive reporting and analysis of all the big

0:26.7

stories out there, the ones that matter most, and to give you a guide to what's happening next up.

0:32.4

Joining us today, super delighted to have Mark Andreessen, the co-founder, general partner of the firm Andresen Horowitz here.

0:39.3

He's one of the smartest people I know.

0:41.3

Let's be honest.

0:41.9

He won't be embarrassed to hear me say it.

0:43.3

When he gets here, we're going to talk about everything under the sun related to AI, China, and the human mind versus the artificial mind, eager to share Mark Endrieson's wisdom with you.

0:56.7

And that's coming up.

0:57.4

But first, my latest reporting and analysis of what's going on here in the country,

1:01.8

so struck by the before and after, before and after Trump.

1:07.5

If you've got kids, this will probably be the best metaphor for you.

1:11.6

People with kids often will say, as I do, can't remember what my life was like before I had a kid or kids, right?

1:18.1

Just changes everything. And Donald Trump has done that too. It's in the abstract possible to remember

1:25.1

before he was in our lives 10 years ago.

1:27.8

But he has been such a dominant presence in our politics,

1:30.7

has affected how both his supporters and detractors think about American politics,

1:37.4

American culture, American economy, that it's a challenge to remember pre-Trump.

1:42.0

And a lot of focus on post-Trump.

1:44.7

Right? Well, I think it's one of the biggest questions we faced in our lifetimes about American politics and American life.

...

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