Lung in a Box: The Present and Future of Lung Preservation for Transplant

Behind The Knife: The Surgery Podcast

Medicine, Health & Fitness, Education, Science

4.8 • 1.4K Ratings

🗓️ 15 July 2024

⏱️ 47 minutes

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Summary

Take a listen into the wild and fascinating world of lung transplantation! One of the biggest challenges for any transplant is organ preservation to provide the best possible recovery and outcome for recipients. That’s especially important for lung transplant, which remains one of the most complex and challenging areas in the field of transplantation. This episode takes a deep dive into the lung transplant landscape and discusses new technologies and innovations that are revolutionizing the field. Jon Williams is joined by Dr. Elliot Wakeam, MD, a thoracic surgeon and lung transplant expert from University of Toronto to discuss the advent of ex-vivo lung perfusion (EVLP) systems and how that and other preservation techniques may impact the future of lung transplantation. Also, Dr. Wakeam provides unique perspectives as faculty from one of the best lung transplant programs in the world.

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Transcript

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0:00.0	Behind the surgery podcast relevant and engaging content designed to help you dominate the day.
0:13.0	Hello and welcome to behind the day.
0:16.0	Hello and welcome to Behind the Night. Today we're going to take a special focus on the highly complex and challenging field of end-stage lung disease and lung transplantations to taking a little bit of a divergence for normal content,
0:33.5	specifically in regard to how new Oregon preservation
0:36.4	technologies have the potential to revolutionize the field
0:39.9	and how it comes for patients with at a stage of lung disease.
0:43.2	If you're a student, resident, or fellow out there
0:44.9	that's ever been involved with a lung transplant,
0:47.6	you probably think of really long arduous complicated cases
0:51.1	that happen in the middle of the night,
0:53.0	and then always being on the lookout for issues
0:55.5	and grab dysfunction afterwards for a pre-Rockey post-operative
0:59.0	course for these patients.
1:00.8	Well, what if I told you that you could always book your lung transplants for a first
1:04.3	star case at 7 the morning the next day? If that sounds like a pipe dream come true or if it
1:09.4	doesn't sound like a dream of yours but you just want to learn more about it.
1:12.8	So, machine profuging of donor organs has certainly become kind of a hot topic and
1:19.0	transplant innovation over the last several years and lungs are no exception to that.
1:23.0	Exhibo lung perfusion or EVLT is a novel lung preservation strategy that
1:28.6	hit the scene for patient use back when it was approved by the FDA in 2018. Today we're going to take a deep dive into
1:35.9	mechanisms of that technology, kind of a little bit of how it came about, how it's used today,
1:41.5	and maybe with some of those implications of that technology or future of lung transplant.
	...

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