Lettuce, Carrots, Soybeans, and Vaccines—Tedrick Thomas Salim Lew—Department of Chemical Engineering at Massachusetts Institute of Technology (MIT)
Finding Genius Podcast
Richard Jacobs
4.4 • 1K Ratings
🗓️ 24 June 2019
⏱️ 34 minutes
🧾️ Download transcript
Summary
What do lettuce, carrots, soybeans, and vaccines have in common? Not much, until now: a team of engineers at MIT have figured out a way to introduce DNA nanoparticles into the chloroplasts of living plants, which has never been done before. Tedrick Thomas Salim Lew, Ph.D., is a member of this team of engineers, and he joins the podcast to discuss why this is so significant, explaining that chloroplasts have previously been impenetrable by any type of material due to the double plasma membrane.
As the site of photosynthesis, having the ability to introduce genetic material into the chloroplast will allow for the chloroplast genome to be modified in a variety of ways, resulting in higher protein production to protect against disease, more efficient use of nutrients, higher growth rates, and perhaps the most surprising of all…the production of human vaccines and hormones, such as the polio vaccine and insulin.
Dr. Tedrick Thomas Salim Lew explains why this method of genetic engineering is far superior to conventional methods, how it will allow for the elimination of costly purification steps in the development of vaccines, new findings in the use of CRISPR-Cas9 in plants and the benefits that this method confers, and where their research is heading.
Transcript
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| 0:00.0 | You're listening to the Future Tech Podcast with Richard Jacobs. |
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| 0:58.0 | Thank you. Hello, this is Richard Jacobs with the Future Tech and Future Tech Health |
| 1:08.5 | Podcast and I have Tedrik Thomas Salim Lou. He's a PhD student at MIT and we're going to be talking about chloroplast gene editing. chloroplast inside of plants. So, |
| 1:19.5 | Tedrick, thanks for being here. How you doing? I'm doing great, Richard. |
| 1:23.0 | Thanks for having me here. |
| 1:24.0 | Yeah, so what's the basis of your research? |
| 1:26.0 | Why are you messing with the chloroplasts of plants? |
| 1:28.0 | Yeah, sure. |
| 1:30.0 | So we work on the delivery on an application of nanomaterials and plants. |
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