Lessons in Longevity: Skincare That Goes Beyond Anti-Aging Featuring Smitha Rao of Parëva Beauty
Skin Anarchy
Ekta et al.
4.2 • 2K Ratings
🗓️ 17 December 2025
⏱️ 42 minutes
🧾️ Download transcript
Summary
In this episode of Skin Anarchy, Dr. Ekta Yadav sits down with Smitha Rao—biotechnologist, longtime beauty innovator, and founder of Pareva Beauty—for a grounded, science-first conversation on what skin longevity actually means. Part of the Lessons in Longevity series, this episode challenges the tired idea of “anti-aging” and reframes skincare as long-term biological support rather than surface-level correction.
With nearly two decades in biotech and beauty, Smitha brings a rare perspective shaped by molecule development, patents licensed across major brands, and leadership roles behind more than 200 products. That experience revealed a growing disconnect: while consumers want clarity and real science, the industry often defaults to hype, fear-based claims, and trend chasing. Pareva Beauty was born as a response—built on transparency, rigor, and the belief that longevity is about extending skin function and resilience, not reversing time.
At the center of the discussion is Molecur 3™, Pareva’s proprietary, plant-based technology inspired by the Hallmarks of Aging. Smitha explains how targeting inflammation, cellular stress, and age-related decline—rather than isolated “anti-aging” claims—creates a more realistic and sustainable path for skin health. The conversation also dives into plant-derived exosomal signaling, why it differs from human-derived systems, and how it offers a safer, scalable approach for topical longevity skincare.
Together, Dr. Ekta and Smitha unpack why fewer, better-designed products outperform complex routines, why transparency matters more than vague “clean” labels, and how longevity skincare must earn trust through data—not promises.
Listen to the full episode to hear how Smitha Rao is helping redefine the future of skincare—where science, honesty, and long-term skin health come first.
Shop Parëva Beauty and use code SA20 for 20% through 3/17.
CHAPTERS:
(0:02) - Introduction, Lessons in Longevity & Smitha Rao
(1:21) - From Biotech to Beauty Innovation
(2:50) - Why Pareva Was Created & The Longevity Gap
(3:33) - Defining Skin Longevity & Extending Your Prime
(5:38) - Rejecting Anti-Aging & Reframing Aging Quality
(8:51) - Molecure 3™: Hallmarks of Aging Inspiration
(10:27) - Plant Stem Cells, NAD⁺ & Exosome Signaling
(14:00) - Exosomes Explained: Plant vs Human-Derived
(22:51) - Simplifying Skincare: Fewer Steps, Better Results
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Transcript
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| 0:00.0 | guys welcome back to another episode of skin anarchy this is a very special and cool episode because |
| 0:04.8 | it's going to be talking about skin care grounded more than just anti-aging claims this is more about |
| 0:11.4 | longevity and i know recently you guys caught our new series which is lessons in longevity which is |
| 0:17.0 | what you're listening to now and and this brand is actually a representation of what |
| 0:22.1 | skincare, you know, what direction skincare is headed when it comes to really helping us understand |
| 0:27.3 | longevity, utilize the tools of longevity in our day-to-day routine. So without further ado, |
| 0:32.2 | I'm going to introduce you guys to Smitha Rao, who is a scientist, first and foremost. She is |
| 0:37.2 | the founder and CEO of Perieva Beauty. Welcome, Smith. I'm so |
| 0:41.0 | excited to host you. Thank you, Exa. Happy to be here. Yeah, I'm really excited to dive in because like I was saying, in the |
| 0:46.9 | intro, longevity is such a new topic, and I feel like consumers want to understand what it means, |
| 0:52.0 | especially with the skin being or a large sorgon, it's very difficult to translate that message. But I love the brand. I love what you're doing. I want to kind of kick things off with you kind of walking us down memory lane and telling us, like, where did the concept for the brand start? And where did your journey begin with skincare? |
| 1:07.8 | Amazing. Let me introduce myself to your audience as well. |
| 1:11.6 | Mara Mitha Rau, I've been in beauty for 18 years. |
| 1:14.6 | I never thought I would be doing what I'm doing. |
| 1:16.6 | I'm classically trained in biotechnology. |
| 1:19.6 | And for the first early part of my career, I created molecules and I have patterns for those |
| 1:25.6 | new innovative molecules that vented to many of the beauty brands that you see today. |
| 1:29.8 | Then I transitioned to be the head of innovation and product development for 15 brands across beauty and wellness. |
| 1:36.7 | Brands like strivetin, sugar bear. |
| 1:39.5 | I consulted for Oliplex. |
| 1:41.3 | So really these frontier innovation-led brands looking at technology, |
| 1:47.0 | looking at very cool new ways to deliver performance to consumers. I've created over 200 products |
... |
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