4.7 • 658 Ratings
🗓️ 12 November 2025
⏱️ 57 minutes
🧾️ Download transcript
Kathy Griffin needs no introduction. This fiery redhead has been making people laugh and causing a ruckus with her unapologetic tea-spilling celebrity anecdotes since the 90s. A self-proclaimed stand-up addict, she joins us in the studio for the first time ever — on her 65th birthday — to talk about her weekly YouTube show, Talk Your Head Off, and her new comedy special, also on YouTube, My Life On the PTSD List. The title is of course a play on her groundbreaking, Emmy-winning reality show My Life On the D List, which was one of the genre and era-defining Bravo shows in the 2000s, and now it’s also on, you guessed it, YouTube. All for free.
We talk about all this, plus her new face (it’s her third), getting thrown out of Paris Hilton’s party, Kris Jenner, body dysmorphia, how she manages to maintain relationships when she’s always being so delightfully, hilariously, and publicly indiscreet. This woman has more comedy specials than any other comedian, man or woman! Plus we discuss Joan Rivers, falling out with Anderson Cooper, Andy Cohen, talking crap about Jerry Seinfeld, Ellen, dating Quentin Tarantino and Steve Wozniak (not at the same time).
We also dig into what was the most seismic moment of her life: when photographer Tyler Shields snapped a shot of her holding up a rubber mask of Trump covered in ketchup. It sparked a chain of overreactions from the President that saw her put on the no-fly list and investigated like a terrorist. So much for free speech! It tanked her career for seven years, and led to a series of really dark periods with drugs and suicidal ideation that also coincided with her losing her mom, the pandemic, getting lung cancer even though she never smoked! Woof. This convo is a wild ride and Zach and Dan definitely get a roasting too.
My Life On the PTSD List | Full Comedy Special ►►https://youtu.be/UF2REkRgUZA?si=UteKJeyZSleZvqM_
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| 0:00.0 | I got my hair makeup on for you. |
| 0:07.7 | I got my lashes on for you. |
| 0:08.9 | You look beautiful. |
| 0:09.6 | I got the hair pieces in. |
| 0:11.4 | You've done the whole thing. |
| 0:13.0 | I've gone, this is kind of a sex kitten look because it's kind of like a fuck you to 65. |
| 0:17.7 | Like I'm a hot 65 year old. |
| 0:19.3 | I say so. |
| 0:20.0 | I'm not saying I'm a hot 20 year old, but I'm a hot 65 year old. Have you seen the market? I'm in the best you're going to get. It's true. Take it. I got to say, I would not assume that you were 65 years old. I've had a little work done. You know, just a smidge. It's okay. What's the matter? Are my hair pieces falling out? |
| 0:39.8 | Sometimes what happens is the fake hair pokes out from the real one. |
| 0:41.6 | And then it's like a |
| 0:43.1 | Sherwood Forest up in there. |
| 0:45.7 | It's like those new Kim Kardashian underwear |
| 0:47.8 | where it's a bush. |
| 0:49.2 | I have that on my head. |
| 0:51.7 | So you literally did come here from Sia's house? |
| 0:54.3 | Mm-hmm. |
| 0:54.8 | And you, |
| 0:55.5 | so this is, you bring us cake and pasty. She got you pasties for your birthday? She got me pasties for my birthday. And, um, she got two kinds of cake. And one of them is one of those crepe cakes, which are very trendy. I've seen them all over TikTok. Yeah, there's a bunch of layers. |
| 1:10.0 | It's a cake out of crapes. |
| 1:10.8 | Yeah, yeah, yeah. |
| 1:11.3 | It defies logic. |
... |
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