5 • 4 Ratings
🗓️ 20 May 2025
⏱️ 22 minutes
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Spinogenix Founder and CEO Stella Sarraf sits with ForbesWomen Editor Maggie McGrath at the Nasdaq MarketSite to discuss her company's novel approach to treating neurodegenerative disease at the synaptic level.
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0:00.0 | Hi everyone, I'm Maggie McGrath, editor of Forbes Women, reporting here from NASDAQ market site. |
0:08.0 | Today, 7 million Americans have Alzheimer's disease, and the Alzheimer's Association expects that number to nearly double within the next 25 years. |
0:19.0 | Within this environment, women are more likely to experience |
0:23.3 | neurocognitive decline than men are, and there is no one cure or treatment that has come to |
0:29.6 | market. Our next guest is trying to change this reality. She is Stella Saraff, the founder and |
0:36.9 | CEO of Spinogenics, a drug discovery and development company |
0:41.0 | that is trying to not just prevent neurocognitive decline, but reverse it in some cases. |
0:47.6 | Stella, thank you so much for being here. |
0:49.3 | Thank you for having me, Maggie. |
0:50.7 | So I don't want to say that your drugs can restore memory because that feels like overstating it a little bit. |
0:56.0 | But can you talk about exactly what you are spearheading through your company? |
0:59.0 | Yeah, I founded Spinogenics in 2016 with the goal to create synaptic regenerative treatments to combat a lot of brain diseases |
1:08.0 | and Alzheimer's being one of the, I would say, one of our big indications that we're very excited for. |
1:13.6 | By working at the synaptic levels, your synapses are the fundamental building blocks that allow your neurons to communicate |
1:20.6 | and actually control the way you plan, think, movement, talking, even sight, and even breathing. |
1:30.3 | So we are very excited because we have a small molecule drug |
1:33.3 | in clinical development working at, restoring those synapses, |
1:37.3 | those connections that stop working. |
1:39.3 | And you can imagine by doing that, |
1:41.3 | when you restore those connections, you can actually regain function. |
1:44.9 | So our hope is that we can restore memory. |
1:47.3 | Our hope is that someone who, let's just say, you still enjoy reading a book, can now pick up a book and actually finish that person with Alzheimer's. |
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