Immunity Mutiny: Demystifying Autoimmunity

Unbiased Science

@unbiasedscipod

Education, Health & Fitness, Science

4.5 • 622 Ratings

🗓️ 9 April 2025

⏱️ 46 minutes

🔗️ Recording | iTunes | RSS

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Summary

In this episode, Dr. Jessica Steier and Dr. Sarah Scheinman welcome Dr. Aimee Pugh Bernard to explore the intricate world of autoimmunity. The scientists examine the fundamental nature of autoimmune disorders, explaining how these conditions develop when the immune system mistakenly attacks healthy tissues. They discuss the challenges in diagnosing these diverse conditions, the critical interplay between genetic predisposition and environmental triggers, and focus on specific examples like celiac disease. The conversation addresses common misconceptions surrounding autoimmune conditions and emphasizes evidence-based approaches to management, while clarifying important questions about the relationship between vaccinations and autoimmune diseases. (00:00) Intro (02:35) Understanding Autoimmunity (08:51) Types of Autoimmune Disorders (11:34) Diagnosis and Testing for Autoimmunity (19:21) Causes and Risk Factors of Autoimmunity (24:25) The Role of Genetics and Environment (25:30) Celiac Disease and Its Unique Aspects (27:23) The Dangers of Misinformation in Autoimmunity (33:23) Understanding Autoimmune Disease Management (40:18) Debunking Myths About Autoimmunity (44:19) Vaccination and Autoimmunity: Facts vs. Fiction https://nationalhealthcouncil.org/blog/a-major-health-crisis-the-alarming-rise-of-autoimmune-disease https://theconversation.com/immune-health-is-all-about-balance-an-immunologist-explains-why-both-too-strong-and-too-weak-an-immune-response-can-lead-to-illness-215217 ----------------------------------------------------------------------------------------------------------------------- Interested in advertising with us? Please reach out to [email protected], with “Unbiased Science” in the subject line. PLEASE NOTE: The discussion and information provided in this podcast are for general educational, scientific, and informational purposes only and are not intended as, and should not be treated as, medical or other professional advice for any particular individual or individuals. Every person and medical issue is different, and diagnosis and treatment requires consideration of specific facts often unique to the individual. As such, the information contained in this podcast should not be used as a substitute for consultation with and/or treatment by a doctor or other medical professional. If you are experiencing any medical issue or have any medical concern, you should consult with a doctor or other medical professional. Further, due to the inherent limitations of a podcast such as this as well as ongoing scientific developments, we do not guarantee the completeness or accuracy of the information or analysis provided in this podcast, although, of course we always endeavor to provide comprehensive information and analysis. In no event may Unbiased Science or any of the participants in this podcast be held liable to the listener or anyone else for any decision allegedly made or action allegedly taken or not taken allegedly in reliance on the discussion or information in this podcast or for any damages allegedly resulting from such reliance. The information provided herein do not represent the views of our employers. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	You're listening to an Airwave Media podcast.
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0:55.6	Music. bias. Welcome to Unbiased Science Science, where we bring scientific method of the madness.
1:00.0	And we're your hosts, Dr. Jess Steyer and Dr. Sarah Scheinman.
1:10.0	And today we are joined by such a special, brilliant, wonderful guest to talk about the topic of autoimmunity.
1:13.3	Dr. Amy Pugh-Bernard, I'm going to read her bio in just a second. Amy is also an unbiased scientist. She regularly contributes to our content. This is such an
1:19.5	honor. She's so brilliant and has studied this topic for many, many years. So Amy, thanks so
1:24.4	much for joining us. Thank you. All right. Let me read this bio, which we
1:29.0	trimmed down significantly. There's a lot to say. So Dr. Amy Pugh-Bernard is an associate
1:34.8	professor in the Department of Immunology and Microbiology at the University of Colorado
1:39.7	and Schutz Medical Campus. She obtained her PhD studying the development.
1:44.8	Hold on.
1:45.4	Let me get this right.
1:46.2	Studying the developmental regulation of human B cells and the autoimmune disease, systemic lupus, arithmeticosis?
1:55.7	No.
1:57.0	Yeah?
	...

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