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Sigma Nutrition Radio

IGF-1 and Diet: Cause For Concern? (SNP36)

Sigma Nutrition Radio

Danny Lennon

Nutrition, Health & Fitness

4.8 • 633 Ratings

🗓️ 8 January 2025

⏱️ 22 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

IGF-1 (Insulin-Like Growth Factor 1) has emerged as a hot topic in health and nutrition discussions, often linked to longevity, cancer risk, and metabolic health.

On one hand, IGF-1 is essential for growth, repair, and metabolic regulation; on the other, it is sometimes associated with disease processes, including cancer and cognitive decline.

For those intrigued by the intersection of nutrition, biomarkers, and disease prevention, IGF-1 offers an opportunity to explore how science grapples with these complexities.

Claims about manipulating IGF-1 through dietary changes — whether by reducing protein or adopting fasting protocols — are common. But does the evidence support these claims?

If you're curious about IGF-1 and the relationships between diet, disease, and healthy aging, in this Premium-exclusive episode Danny and Alan discuss this fascinating topic.

To listen to the full episode, subscribe to Sigma Nutrition Premium

Timestamps

  • [02:21] IGF-1 and Diet: Examining the Relationship
  • [09:15] IGF-1 as a Biomarker: Challenges with Sensitivity and Specificity
  • [11:54] IGF-1 and Cancer Risk: Insights and Complexities
  • [25:51] IGF-1 in Aging: Cognitive Function and Longevity Considerations
  • [43:38] Key Takeaways: IGF-1, Diet, and Practical Advice

Related Resources

Transcript

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0:00.0

Hello and welcome to Sigma Nutrition Radio. As you are currently listening on the public feed of the

0:05.8

podcast, what you're going to listen to today is a preview of one of our premium exclusive episodes.

0:11.5

These are episodes that we publish in their entirety on our Sigma Nutrition Premium podcast feed,

0:17.6

and therefore to listen to that in its entirety, you need to be a Sigma Nutrition

0:21.4

premium subscriber. Being a premium subscriber also gives you a host of other benefits, including

0:26.5

detailed study notes to our podcast episodes and full episode transcripts, as well as other

0:32.7

materials that help you get more from your podcast listening. So take a listen to this preview today. I hope you

0:39.2

enjoy it. And if you want to get these extra bonus podcast episodes in their entirety, as well as those

0:44.7

other benefits, then take a look at Sigma Nutrition Premium, which is linked in the description box

0:49.8

wherever you're currently listening or over on sigmautrition.com slash premium.

0:55.2

See if it's for you, maybe give it a try.

0:57.5

And I think it's really going to enhance how much you learn and retain from these podcast episodes.

1:02.9

So without further ado, please enjoy this preview of today's episode.

1:24.9

Hello and welcome to another episode of Sigma Nutrition Radio. My name is Danny Lennon,

1:27.9

and here with me is Dr. Alan Flanagan. Alan, how are you doing?

1:28.9

I'm very well.

1:35.1

I'm in the throes of our current study, which I think we discussed the hypothesis and what we were intending to do on a previous episode.

1:38.0

So, well, right now we are slapping in the middle of that.

1:41.6

So so far so good.

1:43.3

And then we'll hopefully have some interesting

1:45.5

data to discuss at some point in the spring. Yeah, fantastic. And we certainly look forward to

1:51.7

hearing more about what comes from that. But as from what you've been reporting so far,

...

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