Hypersensitivity Reactions

Medgeeks with Andrew Reid

Medgeeks

Education, Medicine, Health & Fitness

4.8 • 997 Ratings

🗓️ 4 May 2020

⏱️ 10 minutes

🔗️ Recording | iTunes | RSS

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Summary

A 16 year old male is being seen in the ER for cellulitis and a skin abscess. He has already undergone I & D of the abscess and he's waiting to be discharged. You order a shot of Clindamycin, 600mg to be given IM prior to his discharge. Five minutes later, you're called back into the room and you see the patient is in respiratory distress and having very labored breathing. His face is puffy and his voice sounds muffled.

As you consider what to do next, you are struck with a very important question. What type of hypersensitivity reaction is this again? Is it the one with IgE, type 1, type 2, I can't quite remember. Okay, not really that's really not the most important thing at the moment, you know its anaphylaxis, you know that you need to give him Epi; so you draw up 0.5mg and you give it IM, probably saving this guy's life.

So I'll admit maybe the type of hypersensitivity reaction isn't the most clinically relevant information in a crisis situation, but I will say hypersensitivity reactions are high-yield in terms of board review, and they also shed light on the pathophysiology behind many common diseases. Today on the Medgeeks podcast we discuss hypersensitivity reactions.

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Transcript

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0:00.0	A 16 year old male is being seen in the ER for cellulitis and a skin abscess.
0:05.3	He has already undergone I and D of the abscess and he's waiting to be discharged.
0:09.7	You order a shot of klyndomysin, 600 milligrams to be given I. M prior to his discharge.
0:15.8	Five minutes later, you're called back into the room and you see the patient is in respiratory distress
0:20.5	and having very labored breathing. His face is puffy and his voice sounds muffled.
0:25.3	As you consider what to do next you are struck with a very important question.
0:29.2	What type of hypersensitivity reaction is this again? Is it the one with IGE? Type one, type two? I can't
0:37.4	quite remember. Okay not really, that's really not the most important thing at the moment. You know it's anaphylaxis, you know that you need
0:44.8	to give them epi, so you draw 0.5 milligrams and you give it i.m. probably saving this guy's life.
0:50.7	So I'll admit maybe the type of hypersensitivity
0:53.7	reaction isn't the most clinically relevant information in a crisis situation but I
0:58.4	will say hypersensitivity reactions are high yield in terms of board review and they also shed light on the pathoph physiology behind many common diseases.
1:08.0	Today on the Med Geek's podcast we discuss hypersensitivity reactions. Hello everyone and welcome to the med geeks podcast this is your host Eric
1:32.2	speaking today's episode is brought to you by
1:35.6	Tiffany is a student who wrote into us at ask med geeks dot com requesting an episode on
1:41.1	this very topic so So here you go. What are hyper-sensitivity reactions?
1:47.0	Well, let's talk about it. Well, it's basically what happens whenever I get asked for
1:52.2	the 15th time in one day how old I am.
1:55.3	I get hypersensitive about it and I freak out and I get really angry.
1:58.8	I really do have a little bit of a baby face thing going on though. But for real, hypersensitivity reactions. To put it plainly,
2:06.4	it's when the immune system produces an undesirable outcome. It could be considered like the immune system going a little bit overboard.
2:14.4	An exaggerated, inappropriate response of the immune system to some sort of antigen.
	...

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