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The Brian Lehrer Show

HRT and the FDA

The Brian Lehrer Show

WNYC

Arts, Lerer, Radio, York, Wnyc, News, Media, New, Npr, Nyc, Bryan, News Commentary, Politics, Daily News, Public

4.71.4K Ratings

🗓️ 22 July 2025

⏱️ 23 minutes

🧾️ Download transcript

Summary

As the FDA considers removing the warning label from hormone replacement therapy for symptoms of menopause, Jen Gunter, MD, explains the current science and when the risks outweigh the potential benefits.

Transcript

Click on a timestamp to play from that location

0:00.0

It's the Brian Lairn Show on WNYC.

0:12.5

I'm Bridget Bergen, senior reporter in the WNYC in Gothamist Newsroom sitting in for Brian.

0:17.4

Welcome back, everyone.

0:18.8

Have you seen the news that the FDA is calling to remove warning labels

0:22.7

from hormone therapy products used for treating menopause? Currently, all menopause treatments

0:28.2

containing estrogen carry warning labels, noting increased risk of strokes, blood clots, probable

0:34.4

dementia, and breast cancer, regardless of formulation.

0:43.4

Last week, the Food and Drug Administration held a panel in which a dozen physicians and researchers advocated for this change, but some advocates are concerned that the FDA commissioner, Dr. Marty

0:49.9

Mark Carey, and the panel of experts at Thursday's meeting underplayed the risks associated

0:56.6

with hormone treatments. With me now to talk about the risks and benefits of hormonal menopause

1:01.7

treatments and what the possible removal of warning labels could mean for patients and their doctors

1:06.8

is Dr. Jen Gunter. She's an OBGYN and pain medicine physician and author of the books,

1:13.3

The Menopause Manifesto, and Blood, the Science, Medicine, and Mythology of Monstration.

1:19.5

Dr. Gunter, welcome to WNYC.

1:22.7

Thank you for having me.

1:24.4

And before we get into the debate onurling in Washington, can you just

1:28.4

start us off with the basics of this issue? We're talking about hormones here, so it might be

1:32.9

useful to explain the science of menopause, what's going on in the body when we enter menopause,

1:38.8

and why does this happen? Sure. So menopause is the end of ovulation. So puberty is the start of ovulation. Menopause is the end. And we say that a woman is in menopause when she's a year from her final period if she's over the age of 45. Because obviously we don't really know it's your final period until, you know, it's really your final period. There's a time leading up to that final period

2:02.2

that we call the menopause transition that many people call perimenopause. That is associated with

2:08.3

changes in cycles and symptoms can also start then. So in addition to just irregular cycles,

2:14.8

people may have symptoms of menopause starting in their

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