How to Manage Sugar for a Better Brain and a Longer Life – Colleen Cutcliffe, Ph.D. : 943

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

Nutrition, Fitness, Wellness, Fasting, Lifestyle, Meditation, Science, Brain, Hacking, Self-improvement, Fat, Biohacking, Health & Fitness, Education, Diet

4.6 • 7.4K Ratings

🗓️ 3 June 2022

⏱️ 62 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!

Capture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewide

Skin Health and Healing: https://alituranaturals.com/shop/, use code DAVE20 for 20% off storewide

Business Growth With SEO: https://www.stephanspencer.com, get a FREE consultation

SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://pendulumlife.com and use promo code "DAVEVIP" to get an exclusive discount.

IN THIS EPISODE OF THE HUMAN UPGRADE™...

…you’ll learn about emerging science that points to the effects of sugar on your gut microbiome and metabolism and the connections between sugar, your mental acuity and longevity.

Biochemist and molecular biologist Colleen Cutcliffe, Ph.D., continually searches for new ways to improve your gut health and help you live longer. As CEO and co-founder of Pendulum Therapeutics, she works to turn scientific discoveries into real products that hack and heal your microbiome and its associated body systems. At Pendulum, her team identifies and isolates new bacterial strains then combines those new strains to create unique probiotics.

“We really worked hard on ways to modulate post-postprandial glucose spikes through the microbiome,” Colleen says. The result? Pendulum’s Glucose Control lowers blood glucose spikes by 33 to 34% for people with type 2 diabetes. “What we didn't realize was how many people who don't have type 2 diabetes were going to end up benefiting from it.”

This conversation homes in on sugar management and a broad range of research that’s exploring what you can do about managing your glucose to keep up your mental acuity (less brain fog, sharper thinking) and live a longer life.

Science has discovered that as you age:

You have reduced ability to metabolize sugar.
Your microbiomes become less diverse and depleted of certain key strains that are important for sugar metabolism.
If you improve glucose control, you see reduced neuronal inflammation and improved cognition.

In the past decade, especially, sugar dominates a lot of the conversation around diet and health. It’s been studied, substituted, moderated, restricted and demonized. With that type of focus, you lose the bigger point.

“You can't completely cut out sugar,” Colleen says. “You do need sugar. Not all sugar is bad for you all the time. Every cell in your body, except for your colon cells, need glucose in order to survive, in order to replicate, in order to perform functions. All of the things that allow you to be a human being require some amount of sugar."

She wants you to know what’s happening to cause the change in metabolic processing as you age and what you can do about it, like:

How to understand your blood glucose range and what fluctuations mean.
How to track your blood glucose and what to do about peaks and dips.
How to improve your focus, sharpness and mental endurance through diet and fitness.

“I'm a scientist, so I'm always going to say more data is better,” Colleen explains. “[Especially] when you're trying to make improvements and you're making these micro-adjustments in your life, and you want to understand what impact are they having.”

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Transcript

Click on a timestamp to play from that location

0:00.0	You're listening to the human upgrade with Dave Asprey.
0:04.2	Formerly, bulletproof radio.
0:09.0	You're listening to the human upgrade with Dave Asprey.
0:14.8	Today, we are going to be talking about gut metabolism and your microbiome and sugar.
0:24.0	We're going to talk about hacking your brain and how sharp your brain is and how long you're going to live.
0:29.0	And the weird interactions between all of those things.
0:32.0	We're going to go deep on blood glucose range and what fluctuations mean.
0:37.0	And that's because there's been a lot of talk lately about what happens if your blood sugar spikes and then comes down really quickly.
0:43.0	And how important is it to avoid what's called a post-prandial spike?
0:47.0	Strategies to do that and what it can do to other parts of your biology and even different types of blood glucose tracking.
0:54.0	And to the day, though, the goal of this episode is how do you improve your focus, your sharpness and your mental endurance?
1:02.0	So who would be best to talk about this?
1:05.0	Because we know a lot of experts who've been on the show.
1:08.0	Well, Colleen Cutcliffe, who's a PhD and the co-founder of Pendulum Therapeutics, is uniquely well-suited to talk about this intersection of your gut, sugar and your brain.
1:20.0	And as she works all day long on finding new bacterial strains that change your blood sugar response.
1:28.0	In other words, why should you make your body do it when you can have something in your gut do it for you?
1:32.0	And she's very into longevity as well.
1:36.0	And we're going to just figure out the relationship of sugar management, longevity and acuity.
1:42.0	Colleen, welcome back to the show.
1:44.0	Thanks so much for having me.
1:46.0	I love getting a chance to interview you because having the PhD in molecular biology gives you a different mindset than, say, functional medicine doctor or something like that, where you kind of think of it more like an engineer, which I appreciate.
2:03.0	And we've talked about toxins in the gut and gut lining.
	...

Please login to see the full transcript.

Previous episode | Next episode

Disclaimer: The podcast and artwork embedded on this page are from Dave Asprey, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Dave Asprey and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.