4.2 • 639 Ratings
🗓️ 2 May 2017
⏱️ 3 minutes
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0:00.0 | Understanding the human body is a team effort. That's where the Yachtel group comes in. |
0:05.8 | Researchers at Yachtolt have been delving into the secrets of probiotics for 90 years. |
0:11.0 | Yacold also partners with nature portfolio to advance gut microbiome science through the global grants for gut health, an investigator-led research program. |
0:19.6 | To learn more about Yachtolt, visit yawcp.co.j.jot.com.j, that's y-A-K-U-L-T-C-O-J-P. |
0:28.4 | When it comes to a guide for your gut, count on Yacolt. |
0:33.7 | This is Scientific American's 60-second science. I'm Christopher in Taliatta. |
0:38.8 | The ingredient that makes hot chilies hot is called Capsacin, and it can set your mouth on fire. |
0:45.1 | But the spicy compound has a soothing effect, too. In your gut, it kicks off a chemical cascade |
0:49.8 | that might calm the immune system and reduce inflammation. Researchers studied that phenomenon in mice. |
0:56.2 | Once inside the gut, the capsaicin molecule is plugged into a specific receptor, |
1:00.6 | spurring the release of another compound called anandamide. |
1:04.0 | Anandabine happens to be an endocannabinoid, |
1:06.3 | similar to the active ingredients in marijuana, |
1:08.9 | and it binds to cannabinoid receptors in the gut. |
1:11.7 | That last step in the cascade ramped up the production of cells that damped down inflammation |
1:16.2 | in the mice, and even cured them of a mouse model of diabetes type 1, an autoimmune disease. |
1:22.1 | If all this sounds a bit similar to the chemical messaging that happens in the brain, that's because it is. |
1:27.1 | The gut has a very large, well-ard nervous system. It's almost as large as the brain itself. |
1:33.6 | Promotes Ravastava, an immunologist at Yukon Health and one of the studies leaders. |
1:37.8 | We don't quite fully understand what's this huge amount of neurons are doing in the gut. |
1:44.4 | We don't understand its language and the molecules and mediators. |
1:49.1 | And I think with this work, we can at least claim to have found a couple of words in that |
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