Hello and welcome to the zero to finals podcast. My name is Tom and in this episode I'm going to be

talking to you about hormonal access physiology. And if you want to follow along with written notes on

this topic, you can follow along at zero tofinals.com slash endocrinology slash physiology

or in the endocrinology section of the zero

de finals medicine book so let's get straight into it the hypothalamus sits above the

pituitary gland and stimulates it with various hormones the pituitary gland comprises of an

anterior and a posterior section that release separate hormones.

The anterior pejoratory gland releases thyroid-stimulating hormone or T-S-H,

adrenocortica-tropic hormone or A-C-T-H,

follicle stimulating hormone or F-S-H and loutonizing hormone, L-H, growth hormone, or GH, and prolactin.

The posterior pituitary releases oxytocin and antidioretic hormone, or ADH.

The thyroid axis.

The hypothalamus releases

Thyrotrophin releasing hormone, or TRH,

and this stimulates the anterior pituitary gland

to release thyroid-stimulating hormone, or T-S-H.

The thyroid-stimulating hormone, in-S-H. The thyroid-stimulating hormone in turn stimulates the thyroid gland to release tri-iodothyronine or T-3 and thyroxine, which is T-4.

T-3 and T-4 are sensed by the hypothalamus and the anterior pejoratory gland, and they suppress

the release of TRH and Tsh.

This results in lower amounts of T3 and T4 being produced by the thyroid gland.

The lower levels of T3 and T4 offer less suppression to the TRH and the TSAH, and so more of these hormones are released,

resulting in a rise in T3 and T4. In this way, the level of thyroid hormone is closely regulated

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