Histamine Hijack: What Every Woman Needs To Know | Solo

The Dr. Tyna Show

Dr. Tyna Moore

Alternative Health, Health & Fitness

4.9 • 1.4K Ratings

🗓️ 29 May 2025

⏱️ 62 minutes

🔗️ Recording | iTunes | RSS

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Summary

214: In this episode, I’m diving into all things histamine—what it is, how it functions, and why it might be the missing link in your hormone and immune health journey. After sharing insights on the connection between histamine sensitivity and hormone replacement therapy (HRT), the response was massive. I’m unpacking why histamine issues are more than just food reactions, how they relate to estrogen, menopause, and chronic inflammation, and why there’s no one-size-fits-all solution. I’ve dealt with histamine challenges my whole life and supported countless patients through it. This episode is a deep, honest look at the bigger picture behind histamine imbalance. Topics Discussed: What are the symptoms of histamine intolerance and how is it connected to hormone imbalances? How does histamine affect estrogen levels and hormone replacement therapy (HRT)? What causes high histamine levels and how can you support balance naturally? What is the difference between histamine intolerance and mast cell activation syndrome (MCAS)? How do lifestyle factors, diet, and gut health influence histamine sensitivity? Sponsored By: Nutrisense | Head over to nutrisense.io/drtyna to get 30% off your Nutrisense plan. Code TYNA at checkout Puori | Go to Puori.com/drtyna and use code DRTYNA to get 20% off Timeline | Timeline is offering 10% off your order of Mitopure Go to timeline.com/drtyna LVLUP | Head over to LVLUPHealth.com and use code DRTYNA at checkout to get 20% off your order sitewide. LMNT | Get your free Sample Pack with any LMNT purchase at drinkLMNT.com/drtyna Liver Love | Go to https://store.drtyna.com/products/liverlove Use code LIVER20 for 20% off On This Episode Cover: 00:00:00 – Introduction 00:01:57 – Histamine and Your Immune System 00:06:01 – Mast Cells, Allergies, and Inflammation 00:09:55 – My Personal Histamine Story 00:12:38 – Why Histamine Acts Fast 00:15:01 – The Role of Histamine in the Body 00:19:55 – Histamine Intolerance vs. MCAS 00:24:19 – How Menopause Impacts Histamine 00:26:32 – Why Your Histamine Is Out of Balance 00:28:20 – DAO Deficiency Explained 00:32:37 – DAO Blockers and High-Histamine Foods 00:34:32 – Lifestyle Stressors and Chronic Illness 00:36:19 – Common Mast Cell Triggers 00:42:08 – Top High-Histamine Foods 00:43:36 – What Are Histamine Liberators? 00:44:42 – Estrogen, HRT, and Histamine 00:48:10 – Histamine and Metabolic Dysfunction 00:48:34 – Recognizing Histamine-Related Symptoms 00:51:22 – My Clinical Insights on Histamine 00:54:50 – GLP-1 Meds, Histamine, and MCAS Show Links: GLP1 Uncovered Find A Doc Further Listening: EP 41: Dangers of NSAIDS - Solo Episode EP. 199 | Hot Flashes Are a Warning Sign: The Truth About Metabolic Dysfunction | Quick + Dirty EP 106: GLP1 Done Right Part 1 | Solo Episode Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease

Transcript

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0:00.0	You are tuned into the Dr. Tina Show with Dr. Tina Moore. For more, visit Dr. Tina.com.
0:06.3	On this episode of the Dr. Tina show, I am giving you the histamine 101 lesson. I made a post on
0:13.1	Instagram last week. It went bonkers and so many comments. I have not seen that many comments.
0:19.6	I mean, we're well over a thousand or more.
0:22.9	Normally I get a couple hundred. So you guys were very interested in this topic. And then my
0:27.3	DMs blew up simultaneously and emails have been coming in and everybody's wondering,
0:32.4	how do we stabilize the histamine? Because I was talking about HRT and how some people are intolerant to estrogen
0:39.4	and how that may very well be to do with your histamine. And I said the key is you've got to get
0:45.8	your histamine stabilized and then the HRT may stick better or work better or be more tolerated.
0:51.7	And so the big question was how to stabilize histamine.
0:55.7	Unfortunately, there is not a simple answer. So if you want a simple answer, I suggest you sign off now.
1:01.2	This is a very complicated conversation. I am actually going to bring on a histamine expert.
1:06.3	I am not the expert, although I have treated this for decades in my clinic. I live it. I have lived it
1:12.9	since childhood. So I get it. I have a lot of insight on this. I'm going to share that on this
1:17.3	episode today. But as far as treating this goes, it's not a supplement. It's not a pill. There's not
1:22.7	an easy answer. It goes deep. And we have to find the root cause. I'm a naturopathic physician. At the end of the day, we have to find the root cause.
1:29.3	I know that term gets thrown around a lot by health influencers who maybe don't actually
1:32.8	know what it means because you have to have a very deep understanding of physiology and pathophysiology
1:38.9	to understand how to even go backwards down to the root.
1:42.3	So it's kind of like the iceberg. You know, you see this much of it
1:46.0	and then everything down below is really what's happening. And a lot of folks really understand this.
1:50.6	And so when you're hearing about it online, it's like, oh, just treat the parasites or just treat
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