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Science Quickly

High-Sugar Diet Makes Flies Drop Like...Flies

Science Quickly

Scientific American

Science

4.2639 Ratings

🗓️ 23 January 2017

⏱️ 3 minutes

🧾️ Download transcript

Summary

A study examines the effects of a high-sugar diet on the life spans of fruit flies. Another studies how the flies’ appetite-suppressing pathways may be similar to ours. Karen Hopkin reports.  Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

Understanding the human body is a team effort. That's where the Yachtel group comes in.

0:05.8

Researchers at Yachtolt have been delving into the secrets of probiotics for 90 years.

0:11.0

Yacold also partners with nature portfolio to advance gut microbiome science through the global grants for gut health, an investigator-led research program.

0:19.6

To learn more about Yachtolt, visit yawcult.co.

0:22.7

.jp.j. That's y-A-K-U-L-T.C-O.J-P. When it comes to a guide for your gut, count on Yacult.

0:33.6

This is Scientific Americans 60 Second Science.

0:39.1

I'm Karen Hopkins. Got a minute?

0:44.8

I don't believe in all my years I've ever seen a fruit fly I would consider obese.

0:48.8

But thanks to the wonders of modern science, that's all about to change.

0:51.8

Because a team of researchers from Cold Spring Harbor Laboratory has produced the first flies that are genetically engineered to overeat.

0:56.0

If you're wondering why, it's not as silly as it might sound.

1:00.0

A big part of weight control has to do with making healthy dietary choices, and knowing when to step away from the snack cabinet.

1:07.0

But what controls those behaviors?

1:09.0

Well, we humans have a hormone called leptin that

1:12.4

tells us that we're full. After eating, leptin's released from our fat cells, and it travels to our

1:17.6

brains to signal that we've had enough. Indeed, people who don't produce leptin, or who lack

1:22.5

the molecular machinery to detect it, really pack on the pounds. In the new study, researchers discovered a hormone

1:28.5

that acts the same way in flies. And when they deleted the gene that encodes it, the hormonally

1:33.6

deficient insects just kept eating. And when presented with the fly equivalent of a high-fat

1:38.6

or high-sugar diet, they gained three times more weight than did their hormonally competent peers.

1:47.0

The findings appear in the journal Cell Metabolism. Interestingly, giving human leptin to these tubby bugs

1:51.0

eliminates their tendency to binge.

...

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