Hear Me Out: Decibel’s Laurence Reid Discusses Hearing Loss and Potential of Gene Therapy for the Inner Ear
Finding Genius Podcast
Richard Jacobs
4.4 • 1K Ratings
🗓️ 22 February 2022
⏱️ 20 minutes
🧾️ Download transcript
Summary
Nearly 20% of the global population suffers from some level of hearing loss, yet there are still no therapeutics for it on the market – just devices like hearing aids and cochlear implants. The team at Decibel Therapeutics is working to change this.
Lend an ear to learn:
- How different types of hearing loss occur
- What ototoxicity is and how it’s caused by a commonly used chemotherapeutic drug
- Whether gene therapy could be used to correct congenital forms of hearing loss
Laurence Reid is the CEO of Decibel Therapeutics, a company working to develop the very first therapeutics for hearing loss. He joins the show to explain this work in detail, which includes the development of gene therapy products and small-molecule therapeutics. Along the way, he explains the link between cisplatin (a common chemo drug) and hearing loss, and why the products in the Decibel pipeline are looking like promising treatments.
This work has the potential to completely change billions of lives across the globe. If you or someone you know has hearing loss, this episode isn’t one to miss.
Press play to learn more and check out https://www.decibeltx.com/
Episode also available on Apple Podcast: http://apple.co/30PvU9C
Transcript
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| 0:18.0 | Richard Jacobs has made his life's mission to find them for you. |
| 0:22.0 | He hunts down and interviews geniuses in every field. |
| 0:25.0 | Sleep science, cancer, stem cells, ketogenic diets, and more. |
| 0:29.0 | Come the geniuses. |
| 0:30.0 | This is the Finding Genius Podcast. |
| 0:33.0 | Little Richard Jacobs. |
| 0:38.0 | Before we begin, a note from our sponsor. |
| 0:40.0 | I'm Richard Jacobs, executive director of the Nonprofit Finding Genius Foundation, and host |
| 0:45.0 | of the Finding Genius Podcast. |
| 0:46.0 | In late 2016, I was re-rendered at 65 miles an hour by a truck on the highway, which sent |
| 0:52.6 | me off-road into a ditch. |
| 0:54.8 | The impact of the collision gave me a concussion and other injuries. |
| 0:58.0 | At the hospital, a CT scan showed that I had thyroid nodules, which turned out to be cancer. |
| 1:03.0 | It was then when I had a biopsy my neck that I realized, even if I was a million there, |
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