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The Dr. Tyna Show

GLP1s and Dementia: What the Latest Science Shows | Quick + Dirty

The Dr. Tyna Show

Dr. Tyna Moore

Alternative Health, Health & Fitness

4.91.4K Ratings

🗓️ 1 May 2025

⏱️ 19 minutes

🧾️ Download transcript

Summary

EP. 209: In this episode, I’m covering the groundbreaking new data showing a jaw-dropping 45% reduction in dementia risk—and no, it’s not from a new Alzheimer’s drug or expensive intervention. It's from good old GLP-1 medications. I'm walking you through the data, the mechanisms, and what this could mean for your future health.  Topics Discussed:  Recent study: Can GLP-1 medications reduce the risk of dementia? What are the neurocognitive benefits of GLP-1 peptides? Are GLP-1 receptor agonists effective for brain health and memory protection? How do GLP-1s work to prevent cognitive decline or Alzheimer's disease? What does the data show? On This Episode We Cover:  00:00:00 – Introduction 00:03:49 – Neurocognitive benefits of GLP-1s 00:07:35 – Other benefits of GLP-1s 00:13:33 – Biomechanisms of GLP-1s 00:15:06 – Alternative options and final thoughts Show Links:  Cardioprotective Glucose-Lowering Agents and Dementia Risk Further LIstening  GLP1 Uncovered FREE 4 Part Video Series  EP. 207 | Tirzepatide + Metabolic Health: What the Latest Study Really Shows | Solo EP. 208 | This Natural GLP-1 Stimulator Actually Works | Calocurb with Sarah Kennedy Sponsored By: Puori | Go to Puori.com/drtyna and use code DRTYNA to get 20% off LMNT | Get your free Sample Pack with any LMNT purchase at drinkLMNT.com/drtyna Liver Love | Go to https://store.drtyna.com/products/liverlove Use code DRTYNASHOW at checkout to save. Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

Transcript

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0:00.0

You are tuned into the Dr. Tina Show with Dr. Tina Moore. For more, visit Dr. Tina.com.

0:06.2

On this episode of the Dr. Tina show, I'm going to be sharing this study with you that showed

0:11.6

a jaw-dropping 45% reduction in dementia risk, not from some new Alzheimer's drug, not from some fancy intervention, but from good old

0:23.9

GLP-1s.

0:24.9

And I'm so excited to share the data with you.

0:27.3

So let's jump in.

0:29.6

All right.

0:30.3

So this was a very interesting study.

0:32.8

They basically, it was done by two undergrad students, so that right there is very cool.

0:44.7

They looked at 26 randomized control clinical trials, over 164,000 participants.

0:52.9

And this study included patients with type 2 diabetes and cardiovascular risk factors and or, actually. And they looked at different types of blood sugar-lowering drugs like metformin,

0:59.8

GLP-1s, SGLT-2's, SGLT-2 inhibitors, I'm sorry.

1:04.6

And they compared them all, and then they sorted out what cardiovascular benefits were happening and dementia risk.

1:14.1

So the mean age participant was about 65 years old, 64.4 years, I guess 64 years old.

1:20.6

35% were women.

1:23.0

And the average duration follow-up was 31.4 months.

1:29.2

I will say that's a limitation of the study.

1:32.9

They didn't follow up with them very long, and as we know, dementia takes decades to manifest. So there's that. But overall, what they found the key findings were that the

1:39.2

cardioprotective glucose lowering therapies did not significantly reduce the risk of dementia or cognitive

1:45.6

impairment overall.

1:47.1

This is important and I want to reiterate what this means.

1:51.5

Whenever I talk about GLP-1s and their benefits, everybody wants to argue, well, wouldn't

...

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