4.9 • 1.4K Ratings
🗓️ 1 May 2025
⏱️ 19 minutes
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0:00.0 | You are tuned into the Dr. Tina Show with Dr. Tina Moore. For more, visit Dr. Tina.com. |
0:06.2 | On this episode of the Dr. Tina show, I'm going to be sharing this study with you that showed |
0:11.6 | a jaw-dropping 45% reduction in dementia risk, not from some new Alzheimer's drug, not from some fancy intervention, but from good old |
0:23.9 | GLP-1s. |
0:24.9 | And I'm so excited to share the data with you. |
0:27.3 | So let's jump in. |
0:29.6 | All right. |
0:30.3 | So this was a very interesting study. |
0:32.8 | They basically, it was done by two undergrad students, so that right there is very cool. |
0:44.7 | They looked at 26 randomized control clinical trials, over 164,000 participants. |
0:52.9 | And this study included patients with type 2 diabetes and cardiovascular risk factors and or, actually. And they looked at different types of blood sugar-lowering drugs like metformin, |
0:59.8 | GLP-1s, SGLT-2's, SGLT-2 inhibitors, I'm sorry. |
1:04.6 | And they compared them all, and then they sorted out what cardiovascular benefits were happening and dementia risk. |
1:14.1 | So the mean age participant was about 65 years old, 64.4 years, I guess 64 years old. |
1:20.6 | 35% were women. |
1:23.0 | And the average duration follow-up was 31.4 months. |
1:29.2 | I will say that's a limitation of the study. |
1:32.9 | They didn't follow up with them very long, and as we know, dementia takes decades to manifest. So there's that. But overall, what they found the key findings were that the |
1:39.2 | cardioprotective glucose lowering therapies did not significantly reduce the risk of dementia or cognitive |
1:45.6 | impairment overall. |
1:47.1 | This is important and I want to reiterate what this means. |
1:51.5 | Whenever I talk about GLP-1s and their benefits, everybody wants to argue, well, wouldn't |
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