GLP-1s: The New Science Transforming Hormones, Weight Loss, Brain Health, and Beyond

The Liz Moody Podcast

Liz Moody

Health & Fitness, Self-improvement, Education, Mental Health

4.8 • 2.9K Ratings

🗓️ 22 October 2025

⏱️ 95 minutes

🔗️ Recording | iTunes | RSS

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Summary

What if everything you thought GLP-1s were for—was just the beginning? I sit down with Dr. Rocio Salas-Whalen, a board-certified endocrinologist and obesity medicine specialist with over 15 years of experience prescribing GLP-1s, to explore what these medications are really doing in the body. Whether you’re already taking Ozempic or Wegovy, considering starting, or just curious, this conversation will change how you think about metabolism, hormones, and health. Dr. Salas-Whalen explains how GLP-1s go far beyond appetite suppression and weight loss—they can impact fertility, inflammation, autoimmune conditions, and even how your brain responds to addictive cravings and stress. You’ll also hear how body composition, not BMI, is the future of metabolic health, and what to ask your doctor before starting GLP-1s. 👇 Reflect or share: What’s something you thought GLP-1s were only for… that surprised you in this episode? 🎧 What you’ll learn: Why GLP-1s reduce more than appetite—they shift behavior, cravings, and brain chemistry How they’re helping patients with PCOS, insulin resistance, and fertility challenges What inflammation and visceral fat have to do with autoimmune disease How GLP-1s may help during perimenopause and hormonal transitions Why muscle is your strongest anti-inflammatory tool—and how to protect it What the scale doesn’t tell you about your health (and why you need a body comp scan) Dr. Salas-Whalen also shares powerful real-life examples from her practice—like the parent whose child's treatment could break generational cycles of obesity. You’ll walk away with a science-backed, compassionate understanding of GLP-1s that goes way beyond headlines. ✨ Homework: If you're considering GLP-1s, ask yourself: what could change in your life if food noise, weight shame, or inflammation were no longer in the way? If you’ve been waiting to feel more like yourself again—this might be your sign to explore a new path to metabolic health. For more from Dr. Rocio Salas-Whalen: Pre-Order Her Book: Weightless: A Doctor's Guide to GLP-1 Medications, Sustainable Weight Loss, and the Health You Deserve Visit Her Practice: https://www.nyendocrinology.com Her Instagram: https://www.instagram.com/drsalaswhalen Her Facebook: https://www.facebook.com/Dr.RocioSalasWhalen Ready to uplevel every part of your life? Order Liz’s book 100 Ways to Change Your Life: The Science of Leveling Up Health, Happiness, Relationships & Success now! Connect with Liz on Instagram @lizmoody or online at www.lizmoody.com. Subscribe to the substack by visiting https://lizmoody.substack.com/welcome. Buy our cute sweatshirts, conversation cards, and more at https://shop.lizmoody.com/. Use our discount codes from our highly vetted and tested brand partners by visiting https://www.lizmoody.com/codes. To join The Liz Moody Podcast Club Facebook group, go to www.facebook.com/groups/thelizmoodypodcast. This episode is brought to you completely free thanks to the following podcast sponsors: OneSkin: head to OneSkin.co and use the code LIZ for 15% off your purchase. Birch: go to BirchLiving.com/LizMoody for 20% off sitewide. GLW: visit GreatLakesWellness.com and use code LIZMOODY for 25% off your first purchase. The Liz Moody Podcast cover art by Zack. The Liz Moody Podcast music by Alex Ruimy. Formerly the Healthier Together Podcast. This podcast and website represents the opinions of Liz Moody and her guests to the show. The content here should not be taken as medical advice. The content here is for information purposes only, and because each person is so unique, please consult your healthcare professional for any medical questions.The Liz Moody Podcast Episode 375. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	There's been this interesting evolving conversation about using GLP1 medications for things that are way outside of weight loss.
0:07.3	And I'm really, really interested in this research.
0:09.3	I see this clinically.
0:10.8	I have patients that have addictions to drugs that they express that the want is less and also with alcohol.
0:18.3	And it has to do with the reward system.
0:21.4	The patients with PCOS do great on a GLP-1 medication,
0:25.2	and I'm going to tell you why.
0:26.3	A breakthrough moment for me as a doctor in my profession
0:29.5	was to discuss how obesity can be passed from generations,
0:35.3	liberating that girl from guilt.
0:38.0	Hi, I'm Dr. Rosio Salas-Walen, and I'm an endocrinologist and obesity board certified physician.
0:44.1	And I have more than 15 years of clinical experience of using GLP1 on my patients with type 2 diabetes
0:51.2	and obesity.
0:52.1	And I just wrote a book about all of this experience that I've
0:55.6	gathered through the years. Dr. Salas Whalen, I am so excited to have you here. We're going to get
1:00.0	into all of the weight loss and the more commonly talked about things with GLP1s in a second,
1:04.9	but I wanted to start with there's been this interesting evolving conversation about using
1:09.4	GLP1 medications for things that are way
1:12.5	outside of weight loss. And I'm really, really interested in this research. I find it fascinating,
1:17.1	really compelling. So we're going to start with that. We're going to go down the list and kind
1:20.4	of talk about what is the research actually show about using GLP1s for these different conditions.
1:25.7	What have you seen in your practice? What have
	...

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