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Finding Genius Podcast

Gerontologist Berenice Benayoun Reconfigures How We Study Aging

Finding Genius Podcast

Richard Jacobs

Medicine, Health & Fitness

4.41K Ratings

🗓️ 11 June 2020

⏱️ 43 minutes

🧾️ Download transcript

Summary

Professor Benayoun grew interested in studying aging and becoming a gerontologist as an undergraduate working with a key study. Now an assistant professor of gerontology, she explains her current work to listeners.

When you listen, you'll hear her talk about

  • Why it is important that the FDA has not categorized aging as a disease,
  • What transposons have to do with epigenetics, aging, and our immune system, and
  • How differently the sexes respond to the aging process and why that should be centered more in most research.

Berenice A. Benayoun is Assistant Professor of Gerontology at the USC Leonard Davis School of Gerontology. She tells listeners about how she became interested in the field and why it asks such complicated and engaging questions applicable to us all.

She gives some background first on how scientists had to reframe their view on aging after a seminal study by biologist Cynthia Kenyon that found a mutation in a roundworm doubled its life. Benayoun explains that previously aging was thought only in terms of decay, but Kenyon's finding changed this view. 

Benayoun started her own lab at USC about three years ago. She's researching two main concepts, which she explains in more detail: first, her lab is looking at sex differences on aging. She says that some aging interventions have completely different effects on eah sex.

Further, the majority of past studies have steered toward male subjects. Her lab is also looking at transposons, which are endogenous viruses in our genomes, and how they regulate aging. People had thought of them as part of junk DNA in the past, but because they become active when we age, they are likely significant.

She explains other elements of aging that involve epigenetics, methods that show promise for delaying aging such as modulating the insulin cell-signaling pathway, and future steps in her field.

For more see her lab page at gero.usc.edu/labs/benayounlab and find her on twitter as @BBParis1984.

Available on Apple Podcasts: apple.co/2Os0myKhttps://podcasts.apple.com/us/podcast/id1169016854

Transcript

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0:00.0

Forget frequently asked questions.

0:02.0

Common sense, common knowledge, or Google.

0:05.0

How about advice from a real genius?

0:07.0

95% of people in any profession are good enough to be qualified and licensed.

0:11.0

5% go above and beyond. They become very good at what they do, but only 0.1% are real Jesus.

0:18.0

Richard Jacobs has made it his life's mission to find them for you. He hunts down and interviews geniuses in every field, sleep science,

0:25.7

cancer, stem cells, ketogenic diets, and more. Here come the geniuses. This is the Finding Genius

0:32.1

podcast that Richard Jacobs. This is the Finding Genius Podcast.

0:33.0

That is Richard Jacobs.

0:35.0

Hello, this is Richard Jacobs with the Finding Genius Podcast.

0:41.0

I have Perrinise Benayune, I hope I pronounce her name, right?

0:45.4

She's an assistant professor of gerontology at the Leonard Davis School of

0:49.3

Gerontology at USC, also the Norris Comprehensive Cancer Center.

0:54.0

She's part of the USC Stem Cell Initiative.

0:56.4

We're going to talk about aging and all the craziness associated with aging.

1:02.0

So, Bernice, thanks for coming thank you Richard I'm very happy to to be here to talk to you about all of this today

1:11.8

First of all in the field of aging, does it attract older people or does it attract younger people?

1:16.4

And why are you in it?

1:18.4

I mean, it definitely has like a white variety of people interested in aging, and I would say there's actually a lot of young people interested in aging

1:28.0

and that could be like for several reasons one of them being like people who are young or afraid of getting old, you know, and diminished, or just because it's a fascinating question.

1:39.0

Like the reason I got really interested in aging was actually kind of by chance because I did all my undergrad

1:48.5

and grad work in France before I came from my postdoctoral training in the US.

...

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