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Finding Genius Podcast

Fundamental Biology of the T Cell - Your Body's Immune and Inflammatory Response with John Wherry

Finding Genius Podcast

Richard Jacobs

Health, Extracellularvesicles, Crisprcas9, 3dbioprinting, Medicine, Cancer, Health & Fitness, Biotech, Bioscience, Microbiome, Ketogenicdiets

4.41K Ratings

🗓️ 7 April 2022

⏱️ 37 minutes

🧾️ Download transcript

Summary

Why are T cells so vital to our immune response? As one of the primary markers of a potential issue, a problem with your T cells could spell disaster. Listen up to learn:

  • The function of a T cell
  • What T cells recognize
  • How T cell exhaustion can be reversed

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John Wherry, the Chair of the Department of Systems Pharmacology at the University of Pennsylvania, shares his research in epigenetics and the vital role of T cells in our immune system.

T cell differentiation is an essential process in our body, initially being able to control infection and limit tumor growth. However, if the process reaches T cell exhaustion, it can cause a variety of problems in our immune response.

While T cell exhaustion is similar to viruses and tumors, the response can be varied, even if slightly. Still, the reversal of T cell exhaustion has been shown to be effective and will only become more comprehensive as research progresses.

Visit https://www.med.upenn.edu/wherrylab/ for more information.

Episode also available on Apple Podcasts: http://apple.co/30PvU9C

Transcript

Click on a timestamp to play from that location

0:00.0

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0:33.4

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0:38.0

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0:44.3

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0:52.0

Forget frequently asked questions.

0:53.8

Common sense, common knowledge, or Google.

0:56.2

How about advice from a real genius?

0:58.5

95% of people in any profession are good enough to be qualified in license.

1:02.8

5%?

1:03.8

Go above and beyond.

1:04.8

They become very good at what they do, but only 0.1% are real geniuses.

1:09.8

Richard Jacobs has made it his life's mission to find them for you.

1:13.8

He hunts down and interviews geniuses in every field, sleep science, cancer, stem cells,

1:18.6

ketogenic diets, and more.

1:20.2

Here come the geniuses.

...

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