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NutritionFacts.org Video Podcast

Friday Favorites: Fasting to Treat Depression

NutritionFacts.org Video Podcast

Michael Greger, M.D. FACLM

Alternative Health, Health & Fitness, Nutrition

4.8951 Ratings

🗓️ 25 October 2024

⏱️ 6 minutes

🧾️ Download transcript

Summary

Caloric restriction can boost levels of brain-derived neurotrophic factor (BDNF), which is considered to play a critical role in mood disorders.

Transcript

Click on a timestamp to play from that location

0:00.0

For over a century, fasting has been espoused as a treatment of supposed great utility in the preservation of health,

0:16.0

especially rejuvenating the body, but above all, the mind.

0:20.0

But fast people even just 18 hours, and they get all hungry and irritable.

0:25.6

After one or two days, positive mood goes down, negative mood goes up, and by 72 hours,

0:30.6

people can feel sad, self- blaming, and suffer a loss of libido.

0:35.6

But then something strange starts to happen. After a few days, people

0:40.3

experience a fasting-induced mood enhancement, decreased anxiety, depression, fatigue,

0:46.8

and improved vigor. And that's what studies tend to show across the board. Once you get over

0:52.8

the hump, fast faster frequently experience an increased

0:55.3

level of vigilance and mood improvement, a subjective feeling of well-being, sometimes even

1:00.9

euphoria. And no wonder is by then your endorphine levels may shoot up nearly 50%. This

1:08.7

enhancement of mood, alertness, and calm, makes a certain amount of evolutionary sense.

1:13.6

Yet your body wants you to feel crappy initially, so you continue eating day-to-day when food is available.

1:20.6

But if you go a couple days without food, your body realizes that can't have you moping back in the cave,

1:26.6

you've got to get motivated to get out

1:28.6

there and find some calories.

1:31.2

So, can fasting be used for mood disorders like depression?

1:36.5

Yeah, it's great that you can get people to feel better after a few days of fasting,

1:40.2

but the critical question revolves around the persistence of mood improvement over time

1:45.0

once you start eating again.

1:47.0

You don't know until you put it to the test.

1:52.0

Interestingly, the little published evidence we have comes out of Japan and the former Soviet Union,

...

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