Folding DNA into teddy bears and getting creative about gun violence research

Science Magazine Podcast

Science Podcast

News, News Commentary, Science

4.3 • 842 Ratings

🗓️ 7 December 2017

⏱️ 21 minutes

🔗️ Recording | iTunes | RSS

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Summary

This week, three papers came out describing new approaches to folding DNA into large complex shapes—20 times bigger than previous DNA sculptures. Staff Writer Bob Service talks with Sarah Crespi about building microscopic teddy bears, doughnuts, and more from genetic material, and using these techniques to push forward fields from materials science to drug delivery. Sarah also interviews Philip Cook of Duke University in Durham, North Carolina, about his Policy Forum on gun regulation research. It’s long been hard to collect data on gun violence in the United States, and Cook talks about how some researchers are getting funding and hard data. He also discusses some strong early results on open-carry laws and links between gun control and intimate partner homicide. Listen to previous podcasts. [Image: : K. WAGENBAUER ET AL., NATURE, VOL. 551, 2017; Music: Jeffrey Cook] Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	This podcast is supported by the Icon School of Medicine at Mount Sinai,
0:04.0	the academic arm of the Mount Sinai health system in New York City,
0:07.5	and one of America's leading research medical schools.
0:10.7	What are scientists and clinicians working on to improve medical care and health for women?
0:15.5	Find out in a special supplement to Science magazine prepared by the Icon School of Medicine
0:20.0	and Mount Sinai in partnership
0:21.6	with science. Visit our website at www.science.org and search for Frontiers of Medical
0:27.5	Research-Wedmen's Health. The Icon School of Medicine at Mount Sinai, we find a way.
0:42.7	Welcome to the science podcast for December 8, 2017.
0:44.4	I'm Sarah Crespi.
0:50.4	In this week's show, staff writer Bob Service talks about the big news in DNA origami.
0:52.9	It's gotten bigger and cuter.
0:57.3	David Grimm will be back next week. Also this week,
1:04.1	Philip Cook joins us to discuss his policy forum on gun control research. What can science tell us about the effects of open carry laws and links between domestic violence and gun control.
1:16.9	Now we have Bob Servers, Def Writer for Science.
1:22.4	He's here to talk about a piece he wrote on scaling up DNA origami.
1:25.6	Okay, so what is DNA origami? The idea is to make objects out of DNA.
1:29.4	So some shape, a ball or a cube or something that you can then use to do something with.
1:36.1	There's a couple of different ways to do it.
1:37.6	The way that was invented a while back was you make one very long strand of DNA.
1:43.0	And if you recall, DNA is made up of four different
1:47.2	nucleotide bases, A's, G's, C's, and T's. And so when you design your long strand, you dial in a
	...

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