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The Resetter Podcast with Dr. Mindy Pelz

Feed Your Microbiome to Support Your Hormones (& Poop) with Colleen Cutcliffe Ph.D

The Resetter Podcast with Dr. Mindy Pelz

Dr. Mindy Pelz

Guthealth, Environmentaltoxins, Nutrition, Fasting, Keto, Microbiome, Ketogenicdiet, Supplements, Health & Fitness, Biohacking, Healyourself, Alternative Health, Science, Diabetes, Resetterpodcast, Detox, Intermittentfasting, Waterfast, Resetters

4.81.1K Ratings

🗓️ 20 January 2025

⏱️ 62 minutes

🧾️ Download transcript

Summary

Colleen Cutcliffe explores the microbiome's role during menopause, focusing on the estrobolome and gut bacteria's interaction with estrogen. She emphasizes the importance of gut health, particularly Acromantia, and discusses the negative impacts of birth control pills and antibiotics. Along with Dr. Mindy, they highlight essential microbes, dietary changes, and probiotics for wellness, and examine the long-term effects of weight loss drugs on the microbiome. Lastly, they stress measuring health through energy levels and the four pillars of well-being: nutrition, exercise, mental health, and the microbiome.

To view full show notes, more information on our guests, resources mentioned in the episode, discount codes, transcripts, and more, visit https://drmindypelz.com/ep271

Colleen Cutcliffe is the Chief Executive Officer and co-founder of Pendulum. She has more than 15 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotechnology. Prior to starting Pendulum, Colleen was the senior manager of biology at Pacific Biosciences and a scientist at Elan Pharmaceuticals. Colleen completed her postdoctoral studies at Northwestern’s Children’s Memorial Hospital. Colleen received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and her B.A. in Biochemistry from Wellesley College.

Check out our fasting membership at resetacademy.drmindypelz.com.

Please note our medical disclaimer.

Transcript

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0:00.0

On this episode of The Resetter podcast, I am bringing you Colleen Cutcliffe. Now, this is one of those

0:12.4

conversations. I know I say this all the time, but there are certain conversations that I'm

0:17.7

like, you all need to hear this. This is important. I've been trying to find the right person to bring to you.

0:23.6

So let me give you a little background here.

0:25.6

So Colleen Cutliff is the chief executive officer and co-founder of Pendulum.

0:31.6

She has over 15 years of experiencing leading, managing biology teams in academia, pharmaceuticals, biotech, and her

0:39.9

latest passion is the microbiome. She considers herself a scientist, which is how she introduced

0:46.5

herself at this dinner party that I was at. She's completed her postdoctorate studies at Northwestern's

0:53.8

Children's Memorial Hospital.

0:56.1

She has a PhD in biochemistry and molecular biology from John Hopkins and a BA in biochemistry

1:04.9

from Wellesley College. So brilliant woman, incredible discussion, and it's all around the microbiome.

1:12.8

So here's what you're going to hear, and here's what I want you to listen to.

1:16.5

If you've been following me for a while or reading my books, you know that I've talked a lot

1:20.7

about the ostrobalome.

1:22.4

The astrobiome is the set of bacteria that help you take estrogen and metabolize it.

1:30.5

What that means is it'll break down estrogen and make it usable to your cells

1:35.9

so that your cells can activate estrogen into your system.

1:39.7

But one of the challenges I saw in clinical practice and one of the challenges I see with

1:43.9

fasters

1:44.4

and with women going through menopause is that things like poor diet, stress, antibiotics,

1:50.9

birth control pill, certain medications destroy your microbiome.

1:56.0

And then you pop on HRT, you go through the perimenopausal experience, and your hormones go on a wild ride.

...

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